Cited 11 times in
Symptom Interval and Patient Delay Affect Survival Outcomes in Adolescent Cancer Patients.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김선희 | - |
dc.contributor.author | 김효선 | - |
dc.contributor.author | 유철주 | - |
dc.contributor.author | 이윤선 | - |
dc.contributor.author | 진송이 | - |
dc.contributor.author | 한승민 | - |
dc.contributor.author | 한정우 | - |
dc.date.accessioned | 2017-02-27T08:04:01Z | - |
dc.date.available | 2017-02-27T08:04:01Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/147071 | - |
dc.description.abstract | PURPOSE: Unique features of adolescent cancer patients include cancer types, developmental stages, and psychosocial issues. In this study, we evaluated the relationship between diagnostic delay and survival to improve adolescent cancer care. MATERIALS AND METHODS: A total of 592 patients aged 0-18 years with eight common cancers were grouped according to age (adolescents, ≥10 years; children, <10 years). We retrospectively reviewed their symptom intervals (SIs, between first symptom/sign of disease and diagnosis), patient delay (PD, between first symptom/sign of disease and first contact with a physician), patient delay proportion (PDP), and overall survival (OS). RESULTS: Mean SI was significantly longer in adolescents than in children (66.4 days vs. 28.4 days; p<0.001), and OS rates were higher in patients with longer SIs (p=0.001). In children with long SIs, OS did not differ according to PDP (p=0.753). In adolescents with long SIs, OS was worse when PDP was ≥0.6 (67.2%) than <0.6 (95.5%, p=0.007). In a multivariate analysis, adolescents in the long SI/PDP ≥0.6 group tended to have a higher hazard ratio (HR, 6.483; p=0.069) than those in the long SI/PDP <0.6 group (HR=1, reference). CONCLUSION: Adolescents with a long SI/PDP ≥0.6 had lower survival rates than those with a short SI/all PDP or a long SI/PDP <0.6. They should be encouraged to seek prompt medical assistance by a physician or oncologist to lessen PDs. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 572~579 | - |
dc.language | English | - |
dc.publisher | Yonsei University | - |
dc.relation.isPartOf | YONSEI MEDICAL JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Delayed Diagnosis* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Multivariate Analysis | - |
dc.subject.MESH | Neoplasms/classification | - |
dc.subject.MESH | Neoplasms/diagnosis* | - |
dc.subject.MESH | Neoplasms/mortality* | - |
dc.subject.MESH | Neoplasms/psychology | - |
dc.subject.MESH | Patient Acceptance of Health Care/statistics & numerical data* | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Survival Analysis | - |
dc.subject.MESH | Survival Rate | - |
dc.subject.MESH | Time Factors | - |
dc.title | Symptom Interval and Patient Delay Affect Survival Outcomes in Adolescent Cancer Patients. | - |
dc.type | Article | - |
dc.publisher.location | Korea (South) | - |
dc.contributor.college | Others | - |
dc.contributor.department | Severance Hospital | - |
dc.contributor.googleauthor | Song Lee Jin | - |
dc.contributor.googleauthor | Seung Min Hahn | - |
dc.contributor.googleauthor | Hyo Sun Kim | - |
dc.contributor.googleauthor | Yoon Jung Shin | - |
dc.contributor.googleauthor | Sun Hee Kim | - |
dc.contributor.googleauthor | Yoon Sun Lee | - |
dc.contributor.googleauthor | Chuhl Joo Lyu | - |
dc.contributor.googleauthor | Jung Woo Han | - |
dc.identifier.doi | 10.3349/ymj.2016.57.3.572 | - |
dc.contributor.localId | A04527 | - |
dc.contributor.localId | A01201 | - |
dc.contributor.localId | A02524 | - |
dc.contributor.localId | A04634 | - |
dc.contributor.localId | A04688 | - |
dc.contributor.localId | A04299 | - |
dc.contributor.localId | A04325 | - |
dc.relation.journalcode | J02813 | - |
dc.identifier.eissn | 1976-2437 | - |
dc.identifier.pmid | 26996554 | - |
dc.subject.keyword | Adolescent cancer patients | - |
dc.subject.keyword | patient delay | - |
dc.subject.keyword | symptom interval | - |
dc.contributor.alternativeName | Kim, Sun Hee | - |
dc.contributor.alternativeName | Kim, Hyo Sun | - |
dc.contributor.alternativeName | Lyu, Chuhl Joo | - |
dc.contributor.alternativeName | Ree, Yoon Sun | - |
dc.contributor.alternativeName | Jin, Song Lee | - |
dc.contributor.alternativeName | Hahn, Seung Min | - |
dc.contributor.alternativeName | Han, Jung Woo | - |
dc.contributor.affiliatedAuthor | Kim, Sun Hee | - |
dc.contributor.affiliatedAuthor | Kim, Hyo Sun | - |
dc.contributor.affiliatedAuthor | Lyu, Chuhl Joo | - |
dc.contributor.affiliatedAuthor | Ree, Yoon Sun | - |
dc.contributor.affiliatedAuthor | Jin, Song Lee | - |
dc.contributor.affiliatedAuthor | Hahn, Seung Min | - |
dc.contributor.affiliatedAuthor | Han, Jung Woo | - |
dc.citation.volume | 57 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 572 | - |
dc.citation.endPage | 579 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, Vol.57(3) : 572-579, 2016 | - |
dc.date.modified | 2017-02-24 | - |
dc.identifier.rimsid | 47103 | - |
dc.type.rims | ART | - |
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