0 1119

Cited 18 times in

Is the recent WHO histological classification for gastric cancer helpful for application to endoscopic resection?

DC Field Value Language
dc.contributor.author김지현-
dc.contributor.author박효진-
dc.contributor.author신성관-
dc.contributor.author김현기-
dc.contributor.author김호근-
dc.contributor.author노성훈-
dc.contributor.author박재준-
dc.contributor.author박준철-
dc.contributor.author윤영훈-
dc.contributor.author이상길-
dc.contributor.author이용찬-
dc.contributor.author정현수-
dc.contributor.author최승호-
dc.date.accessioned2017-02-27T07:57:17Z-
dc.date.available2017-02-27T07:57:17Z-
dc.date.issued2016-
dc.identifier.issn1436-3291-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/147041-
dc.description.abstractBACKGROUND: Endoscopic resection is performed in undifferentiated-type early gastric cancer (UD-EGC), including poorly differentiated (PD) adenocarcinoma and signet ring cell (SRC) carcinoma. We previously found that different approaches are needed for PD adenocarcinoma and SRC carcinoma for curative resection. However, according to the 2010 WHO classification, diffuse-type PD adenocarcinoma and SRC carcinoma are categorized in the "poorly cohesive carcinomas." Thus, we assessed whether the WHO classification is helpful when endoscopic resection is performed for treatment of UD-EGC. METHODS: We analyzed clinicopathological features of 1295 lesions with SRC carcinoma and PD adenocarcinoma treated by open surgery. We recategorized them into intestinal-type PD adenocarcinomas and poorly cohesive carcinomas (SRC carcinoma, diffuse-type PD adenocarcinoma). We also recategorized 176 lesions treated by endoscopic resection into intestinal-type PD adenocarcinomas and poorly cohesive carcinomas. RESULTS: According to the open surgery data, the rates of lymph node metastasis (LNM) and lymphovascular invasion were significantly lower in SRC carcinoma than in diffuse-type and intestinal-type PD adenocarcinomas. The rates of LNM and lymphovascular invasion were significantly higher in diffuse-type PD adenocarcinoma than in SRC carcinoma. Endoscopic resection data showed no recurrence if the carcinoma was curatively resected. However, the commonest cause of noncurative resection was different in SRC carcinoma and PD adenocarcinoma. A positive lateral margin was the commonest cause in SRC carcinoma versus a positive vertical margin in both intestinal-type and diffuse-type PD adenocarcinoma. CONCLUSIONS: The clinical behavior differs in diffuse-type PD adenocarcinoma and SRC carcinoma. On the basis of LNM and outcomes of endoscopic resection, the recent WHO classification may not be helpful when endoscopic resection is performed for treatment of UD-EGC.-
dc.description.statementOfResponsibilityrestriction-
dc.format.extent869~875-
dc.languageEnglish-
dc.publisherSpringer-Verlag Tokyo-
dc.relation.isPartOfGASTRIC CANCER-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdenocarcinoma/classification-
dc.subject.MESHAdenocarcinoma/secondary*-
dc.subject.MESHAdenocarcinoma/surgery-
dc.subject.MESHCarcinoma, Signet Ring Cell/classification-
dc.subject.MESHCarcinoma, Signet Ring Cell/secondary*-
dc.subject.MESHCarcinoma, Signet Ring Cell/surgery-
dc.subject.MESHEndoscopy Female-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHGastric Mucosa/pathology*-
dc.subject.MESHGastroscopy-
dc.subject.MESHHumans-
dc.subject.MESHLymphatic Metastasis-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeoplasm Grading-
dc.subject.MESHNeoplasm Invasiveness-
dc.subject.MESHPrognosis-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHStomach Neoplasms/classification-
dc.subject.MESHStomach Neoplasms/pathology*-
dc.subject.MESHStomach Neoplasms/surgery-
dc.subject.MESHWorld Health Organization-
dc.titleIs the recent WHO histological classification for gastric cancer helpful for application to endoscopic resection?-
dc.typeArticle-
dc.publisher.locationJapan-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Internal Medicine-
dc.contributor.googleauthorYong Hoon Kim-
dc.contributor.googleauthorJie-Hyun Kim-
dc.contributor.googleauthorHyunKi Kim-
dc.contributor.googleauthorHoguen Kim-
dc.contributor.googleauthorYong Chan Lee-
dc.contributor.googleauthorSang Kil Lee-
dc.contributor.googleauthorSung Kwan Shin-
dc.contributor.googleauthorJun Chul Park-
dc.contributor.googleauthorHyun Soo Chung-
dc.contributor.googleauthorJae Jun Park-
dc.contributor.googleauthorYoung Hoon Youn-
dc.contributor.googleauthorHyojin Park-
dc.contributor.googleauthorSung Hoon Noh-
dc.contributor.googleauthorSeung Ho Choi-
dc.identifier.doi10.1007/s10120-015-0538-4-
dc.contributor.localIdA00996-
dc.contributor.localIdA01774-
dc.contributor.localIdA02112-
dc.contributor.localIdA01108-
dc.contributor.localIdA01183-
dc.contributor.localIdA01281-
dc.contributor.localIdA01636-
dc.contributor.localIdA01676-
dc.contributor.localIdA02583-
dc.contributor.localIdA02812-
dc.contributor.localIdA02988-
dc.contributor.localIdA03765-
dc.contributor.localIdA04102-
dc.relation.journalcodeJ00916-
dc.identifier.eissn1436-3305-
dc.identifier.pmid26324820-
dc.identifier.urlhttp://link.springer.com/article/10.1007/s10120-015-0538-4-
dc.subject.keywordEarly gastric cancer-
dc.subject.keywordEndoscopic resection-
dc.subject.keywordLymph node metastasis-
dc.subject.keywordUndifferentiated-
dc.contributor.alternativeNameKim, Ji Hyun-
dc.contributor.alternativeNamePark, Hyo Jin-
dc.contributor.alternativeNameShin, Sung Kwan-
dc.contributor.alternativeNameKim, Hyun Ki-
dc.contributor.alternativeNameKim, Ho Keun-
dc.contributor.alternativeNameNoh, Sung Hoon-
dc.contributor.alternativeNamePark, Jae Jun-
dc.contributor.alternativeNamePark, Jun Chul-
dc.contributor.alternativeNameYoun, Young Hoon-
dc.contributor.alternativeNameLee, Sang Kil-
dc.contributor.alternativeNameLee, Yong Chan-
dc.contributor.alternativeNameChung, Hyun Soo-
dc.contributor.alternativeNameChoi, Seung Ho-
dc.contributor.affiliatedAuthorKim, Ji Hyun-
dc.contributor.affiliatedAuthorPark, Hyo Jin-
dc.contributor.affiliatedAuthorShin, Sung Kwan-
dc.contributor.affiliatedAuthorKim, Hyun Ki-
dc.contributor.affiliatedAuthorKim, Ho Keun-
dc.contributor.affiliatedAuthorNoh, Sung Hoon-
dc.contributor.affiliatedAuthorPark, Jae Jun-
dc.contributor.affiliatedAuthorPark, Jun Chul-
dc.contributor.affiliatedAuthorYoun, Young Hoon-
dc.contributor.affiliatedAuthorLee, Sang Kil-
dc.contributor.affiliatedAuthorLee, Yong Chan-
dc.contributor.affiliatedAuthorChung, Hyun Soo-
dc.contributor.affiliatedAuthorChoi, Seung Ho-
dc.citation.volume19-
dc.citation.number3-
dc.citation.startPage869-
dc.citation.endPage875-
dc.identifier.bibliographicCitationGASTRIC CANCER, Vol.19(3) : 869-875, 2016-
dc.date.modified2017-02-24-
dc.identifier.rimsid47073-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.