Cited 13 times in
Hyponatremia in patients with systemic lupus erythematosus
DC Field | Value | Language |
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dc.contributor.author | 김동수 | - |
dc.contributor.author | 김지홍 | - |
dc.contributor.author | 신재일 | - |
dc.contributor.author | 이금화 | - |
dc.contributor.author | 한송이 | - |
dc.date.accessioned | 2017-02-27T07:55:23Z | - |
dc.date.available | 2017-02-27T07:55:23Z | - |
dc.date.issued | 2016 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/147034 | - |
dc.description.abstract | The aim of this study was to determine whether decreased serum sodium concentration could be associated with the disease activity in SLE. We retrospectively analyzed the data of the two independent cohorts of children and adults with SLE in two centers. Hyponatremia was associated with serum chloride (p = 0.004), albumin (p = 0.002) and SLE disease activity index (SLEDAI) (p = 0.026) in children with SLE. Serum sodium levels were correlated negatively with ESR (p =0.001) and positively with serum albumin levels (p < 0.0001) and C3 (p = 0.008) in children with SLE and those levels were correlated negatively with serum interleukin-6 levels (p = 0.003) in adults with SLE. Independent risk factors for the development of hyponatremia were the decreased serum C3 levels (OR 1.069, p = 0.031), the decreased serum chloride levels (OR 2.054, p = 0.006) and increased erythrocyte sedimentation rate (ESR) (OR 1.066, p = 0.03) in children with SLE and increased C-reactive protein (CRP) (OR 1.480, p = 0.023) in combined cohorts with SLE by multiple logistic regression analyses. Our study firstly showed that hyponatremia could reflect a disease activity and severe inflammation of SLE. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Nature Publishing Group | - |
dc.relation.isPartOf | SCIENTIFIC REPORTS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Blood Sedimentation | - |
dc.subject.MESH | C-Reactive Protein/metabolism | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | Chlorides/blood* | - |
dc.subject.MESH | Complement C3/metabolism | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hyponatremia/blood* | - |
dc.subject.MESH | Infant | - |
dc.subject.MESH | Inflammation/blood | - |
dc.subject.MESH | Inflammation/pathology | - |
dc.subject.MESH | Lupus Erythematosus, Systemic/blood* | - |
dc.subject.MESH | Lupus Erythematosus, Systemic/pathology | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Serum Albumin/metabolism* | - |
dc.subject.MESH | Sodium/blood* | - |
dc.subject.MESH | Young Adult | - |
dc.title | Hyponatremia in patients with systemic lupus erythematosus | - |
dc.type | Article | - |
dc.publisher.location | England | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Pediatrics | - |
dc.contributor.googleauthor | Jae Il Shin | - |
dc.contributor.googleauthor | Se Jin Park | - |
dc.contributor.googleauthor | Chang-Hee Suh | - |
dc.contributor.googleauthor | Geum Hwa Lee | - |
dc.contributor.googleauthor | Min Woo Hur | - |
dc.contributor.googleauthor | Song Yi Han | - |
dc.contributor.googleauthor | Dong Soo Kim | - |
dc.contributor.googleauthor | Ji Hong Kim | - |
dc.identifier.doi | 10.1038/srep25566 | - |
dc.contributor.localId | A00405 | - |
dc.contributor.localId | A01003 | - |
dc.contributor.localId | A02142 | - |
dc.contributor.localId | A04622 | - |
dc.contributor.localId | A04699 | - |
dc.relation.journalcode | J02646 | - |
dc.identifier.eissn | 2045-2322 | - |
dc.identifier.pmid | 27193532 | - |
dc.contributor.alternativeName | Kim, Dong Soo | - |
dc.contributor.alternativeName | Kim, Ji Hong | - |
dc.contributor.alternativeName | Shin, Jae Il | - |
dc.contributor.alternativeName | Lee, Geum Hwa | - |
dc.contributor.alternativeName | Han, Song Yi | - |
dc.contributor.affiliatedAuthor | Kim, Dong Soo | - |
dc.contributor.affiliatedAuthor | Kim, Ji Hong | - |
dc.contributor.affiliatedAuthor | Shin, Jae Il | - |
dc.contributor.affiliatedAuthor | Lee, Geum Hwa | - |
dc.contributor.affiliatedAuthor | Han, Song Yi | - |
dc.citation.volume | 6 | - |
dc.citation.startPage | 25566 | - |
dc.identifier.bibliographicCitation | SCIENTIFIC REPORTS, Vol.6 : 25566, 2016 | - |
dc.date.modified | 2017-02-24 | - |
dc.identifier.rimsid | 47066 | - |
dc.type.rims | ART | - |
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