Cited 23 times in
Renal denervation for treatment of uncontrolled hypertension in an Asian population: results from the Global SYMPLICITY Registry in South Korea (GSR Korea).
DC Field | Value | Language |
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dc.contributor.author | 권혁문 | - |
dc.contributor.author | 김병극 | - |
dc.contributor.author | 박성하 | - |
dc.contributor.author | 장양수 | - |
dc.contributor.author | 홍명기 | - |
dc.date.accessioned | 2017-02-24T11:48:34Z | - |
dc.date.available | 2017-02-24T11:48:34Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 0950-9240 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/146868 | - |
dc.description.abstract | Reports detailing the response of hypertensive patients to renal denervation (RDN) in Asian patients are limited. We evaluated 6- and 12-month outcomes after RDN in an Asian population and compared outcomes to a primarily Caucasian population. The Global SYMPLICITY Registry (GSR) is a prospective, all-comer, worldwide registry that evaluates the safety and effectiveness of RDN and includes the Korean registry substudy (GSR Korea) and a Caucasian subset (GSR Caucasian). Given differences in baseline characteristics among GSR Korea (n=93) as compared with GSR Caucasian (n=169) patients, including lower baseline office systolic blood pressure (SBP), lower body mass index and differences in medications, propensity score adjustment was performed when comparing the change in SBP between subsets. The 6- and 12-month change in SBP in GSR Korea was -19.4±17.2 and -27.2±18.1 mm Hg, respectively (P<0.001 for both vs baseline). GSR Caucasian had a SBP change similar to GSR Korea at 6 months (-20.9±21.4 mm Hg, unadjusted P=0.547, adjusted P=0.998), whereas at 12 months the change was significantly less pronounced (-20.1±23.9 mm Hg, unadjusted P=0.004, adjusted P=0.002). There were no protocol-defined procedure-related adverse events and no chronic adverse events associated with the device in an Asian population. RDN provided a significant reduction in 6- and 12-month office SBP among Asian patients, with a favorable safety profile. The 12-month SBP reduction was larger than that observed in Caucasian patients. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.format.extent | 315~321 | - |
dc.language | English | - |
dc.publisher | Nature Publishing Group | - |
dc.relation.isPartOf | JOURNAL OF HUMAN HYPERTENSION | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Antihypertensive Agents/therapeutic use | - |
dc.subject.MESH | Blood Pressure | - |
dc.subject.MESH | Catheter Ablation/statistics & numerical data* | - |
dc.subject.MESH | Denervation/statistics & numerical data* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hypertension/drug therapy | - |
dc.subject.MESH | Hypertension/surgery* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Registries* | - |
dc.subject.MESH | Renal Artery/innervation* | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Renal denervation for treatment of uncontrolled hypertension in an Asian population: results from the Global SYMPLICITY Registry in South Korea (GSR Korea). | - |
dc.type | Article | - |
dc.publisher.location | England | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Internal Medicine | - |
dc.contributor.googleauthor | B-K Kim | - |
dc.contributor.googleauthor | M Böhm | - |
dc.contributor.googleauthor | F Mahfoud | - |
dc.contributor.googleauthor | G Mancia | - |
dc.contributor.googleauthor | S Park | - |
dc.contributor.googleauthor | M-K Hong | - |
dc.contributor.googleauthor | H-S Kim | - |
dc.contributor.googleauthor | S-J Park | - |
dc.contributor.googleauthor | CG Park | - |
dc.contributor.googleauthor | KB Seung | - |
dc.contributor.googleauthor | H-C Gwon | - |
dc.contributor.googleauthor | D-J Choi | - |
dc.contributor.googleauthor | TH Ahn | - |
dc.contributor.googleauthor | CJ Kim | - |
dc.contributor.googleauthor | HM Kwon | - |
dc.contributor.googleauthor | M Esler | - |
dc.contributor.googleauthor | YS Jang | - |
dc.identifier.doi | 10.1038/jhh.2015.77 | - |
dc.contributor.localId | A00260 | - |
dc.contributor.localId | A00493 | - |
dc.contributor.localId | A01512 | - |
dc.contributor.localId | A03448 | - |
dc.contributor.localId | A04391 | - |
dc.relation.journalcode | J01447 | - |
dc.identifier.eissn | 1476-5527 | - |
dc.identifier.pmid | 26155994 | - |
dc.identifier.url | http://www.nature.com/jhh/journal/v30/n5/full/jhh201577a.html | - |
dc.contributor.alternativeName | Kwon, Hyuck Moon | - |
dc.contributor.alternativeName | Kim, Byeong Keuk | - |
dc.contributor.alternativeName | Park, Sung Ha | - |
dc.contributor.alternativeName | Jang, Yang Soo | - |
dc.contributor.alternativeName | Hong, Myeong Ki | - |
dc.contributor.affiliatedAuthor | Kwon, Hyuck Moon | - |
dc.contributor.affiliatedAuthor | Kim, Byeong Keuk | - |
dc.contributor.affiliatedAuthor | Park, Sung Ha | - |
dc.contributor.affiliatedAuthor | Jang, Yang Soo | - |
dc.contributor.affiliatedAuthor | Hong, Myeong Ki | - |
dc.citation.volume | 30 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 315 | - |
dc.citation.endPage | 321 | - |
dc.identifier.bibliographicCitation | JOURNAL OF HUMAN HYPERTENSION, Vol.30(5) : 315-321, 2016 | - |
dc.date.modified | 2017-02-24 | - |
dc.identifier.rimsid | 47962 | - |
dc.type.rims | ART | - |
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