Cited 21 times in
Comparison and Validation of 10 Equations Including a Novel Method for Estimation of LDL-cholesterol in a 168,212 Asian Population
DC Field | Value | Language |
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dc.contributor.author | 강은석 | - |
dc.contributor.author | 김정호 | - |
dc.contributor.author | 김하얀 | - |
dc.contributor.author | 이병완 | - |
dc.contributor.author | 이상국 | - |
dc.contributor.author | 이용호 | - |
dc.contributor.author | 임정훈 | - |
dc.contributor.author | 차봉수 | - |
dc.date.accessioned | 2017-02-24T11:42:37Z | - |
dc.date.available | 2017-02-24T11:42:37Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 0025-7974 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/146839 | - |
dc.description.abstract | Low-density lipoprotein cholesterol (LDL-C) is frequently estimated using the empirical Friedewald equation. We compared the accuracy of the novel equation named as the 180-cell method (180-c), which estimates LDL-C using a stratification approach, to those of 9 previously suggested formulas, including the Friedewald equation.We compared the accuracy of 10 equations by calculating intraclass correlation coefficient (ICC) and weighted kappa index in relation to direct LDL-C measurement values. Two independent populations used in the validation were the Severance Hospital LDL-C (SHL) registry (n = 164,358) and the Korea National Health and Nutrition Examination Survey (KNHANES) 2009 to 2010 (n = 3,854), each representing the hospital patient population and the general Korean population, respectively.The 180-c and DeLong equations showed the highest ICCs, indicating the best agreement with direct LDL-C measurement. The 180-c and Chen equations showed the highest kappa indices. For the hypertriglyceridemic subpopulation from SHL, the 180-c equation showed the best agreement with direct LDL-C measurement in terms of ICC.We compared the novel 180-c method for LDL-C estimation with 9 previous formulas in a non-US population as the first external validation. The 180-c equation, with Chen equation, appeared to be more accurate than the Friedewald equation. Although the DeLong equation showed better performance in the hypertriglyceridemic subpopulation, the 180-c equation performed appropriately in Asian population. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Lippincott Williams & Wilkins | - |
dc.relation.isPartOf | MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Asian Continental Ancestry Group | - |
dc.subject.MESH | Cholesterol, LDL/blood* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Mathematical Concepts | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Young Adult | - |
dc.title | Comparison and Validation of 10 Equations Including a Novel Method for Estimation of LDL-cholesterol in a 168,212 Asian Population | - |
dc.type | Article | - |
dc.publisher.location | United States | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Internal Medicine | - |
dc.contributor.googleauthor | John Hoon Rim | - |
dc.contributor.googleauthor | Yong-ho Lee | - |
dc.contributor.googleauthor | Myung Ha Lee | - |
dc.contributor.googleauthor | Ha Yan Kim | - |
dc.contributor.googleauthor | Jiin Choi | - |
dc.contributor.googleauthor | Byung-Wan Lee | - |
dc.contributor.googleauthor | Eun Seok Kang | - |
dc.contributor.googleauthor | Hyun Chul Lee | - |
dc.contributor.googleauthor | Jeong-Ho Kim | - |
dc.contributor.googleauthor | Sang-Guk Lee | - |
dc.contributor.googleauthor | Bong-Soo Cha | - |
dc.identifier.doi | 10.1097/MD.0000000000003230 | - |
dc.contributor.localId | A00068 | - |
dc.contributor.localId | A00903 | - |
dc.contributor.localId | A01091 | - |
dc.contributor.localId | A02796 | - |
dc.contributor.localId | A02810 | - |
dc.contributor.localId | A02989 | - |
dc.contributor.localId | A04654 | - |
dc.contributor.localId | A03996 | - |
dc.relation.journalcode | J02214 | - |
dc.identifier.eissn | 1536-5964 | - |
dc.identifier.pmid | 27057857 | - |
dc.contributor.alternativeName | Kang, Eun Seok | - |
dc.contributor.alternativeName | Kim, Jeong Ho | - |
dc.contributor.alternativeName | Kim, Ha Yan | - |
dc.contributor.alternativeName | Lee, Byung Wan | - |
dc.contributor.alternativeName | Lee, Sang Guk | - |
dc.contributor.alternativeName | Lee, Yong Ho | - |
dc.contributor.alternativeName | Rim, John Hoon | - |
dc.contributor.alternativeName | Cha, Bong Soo | - |
dc.contributor.affiliatedAuthor | Kang, Eun Seok | - |
dc.contributor.affiliatedAuthor | Kim, Jeong Ho | - |
dc.contributor.affiliatedAuthor | Kim, Ha Yan | - |
dc.contributor.affiliatedAuthor | Lee, Byung Wan | - |
dc.contributor.affiliatedAuthor | Lee, Sang Guk | - |
dc.contributor.affiliatedAuthor | Lee, Yong Ho | - |
dc.contributor.affiliatedAuthor | Rim, John Hoon | - |
dc.contributor.affiliatedAuthor | Cha, Bong Soo | - |
dc.citation.volume | 95 | - |
dc.citation.number | 14 | - |
dc.citation.startPage | 3230 | - |
dc.identifier.bibliographicCitation | MEDICINE, Vol.95(14) : 3230, 2016 | - |
dc.date.modified | 2017-02-24 | - |
dc.identifier.rimsid | 47581 | - |
dc.type.rims | ART | - |
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