Cited 14 times in
Bone Regeneration Using a Mixture of Silicon-Substituted Coral HA and β-TCP in a Rat Calvarial Bone Defect Model
DC Field | Value | Language |
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dc.contributor.author | 김경남 | - |
dc.contributor.author | 김광만 | - |
dc.date.accessioned | 2017-02-24T11:24:26Z | - |
dc.date.available | 2017-02-24T11:24:26Z | - |
dc.date.issued | 2016 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/146759 | - |
dc.description.abstract | The demand of bone graft materials has been increasing. Among various origins of bone graft materials, natural coral composed of up to 99% calcium carbonate was chosen and converted into hydroxyapatite (HA); silicon was then substituted into the HA. Then, the Si-HA was mixed with β-tricalcium phosphate (TCP) in the ratios 100:0 (S100T0), 70:30 (S70T30), 60:40 (S60T40), and 50:50 (S50T50). The materials were implanted for four and eight weeks in a rat calvarial bone defect model (8 mm). The MBCPTM (HA:β-TCP = 60:40, Biomatalante, Vigneux de Bretagne, France) was used as a control. After euthanasia, the bone tissue was analyzed by making histological slides. From the results, S60T40 showed the fastest bone regeneration in four weeks (p < 0.05). In addition, S60T40, S50T50, and MBCPTM showed significant new bone formation in eight weeks (p < 0.05). In conclusion, Si-HA/TCP showed potential as a bone graft material. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | MDPI | - |
dc.relation.isPartOf | MATERIALS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Bone Regeneration Using a Mixture of Silicon-Substituted Coral HA and β-TCP in a Rat Calvarial Bone Defect Model | - |
dc.type | Article | - |
dc.publisher.location | Switzerland | - |
dc.contributor.college | College of Dentistry | - |
dc.contributor.department | Dept. of Dental Engineering | - |
dc.contributor.googleauthor | Jiyeon Roh | - |
dc.contributor.googleauthor | Ji-Youn Kim | - |
dc.contributor.googleauthor | Young-Muk Choi | - |
dc.contributor.googleauthor | Seong-Min Ha | - |
dc.contributor.googleauthor | Kyoung-Nam Kim | - |
dc.contributor.googleauthor | Kwang-Mahn Kim | - |
dc.identifier.doi | 10.3390/ma9020097 | - |
dc.contributor.localId | A00292 | - |
dc.contributor.localId | A00312 | - |
dc.relation.journalcode | J02182 | - |
dc.identifier.eissn | 1996-1944 | - |
dc.identifier.pmid | 28787903 | - |
dc.subject.keyword | beta-tricalcium phosphate | - |
dc.subject.keyword | bone graft material | - |
dc.subject.keyword | bone regeneration | - |
dc.subject.keyword | rat calvarial bone defect model | - |
dc.subject.keyword | silicon-substituted coral hydroxyapatite | - |
dc.contributor.alternativeName | Kim, Kyoung Nam | - |
dc.contributor.alternativeName | Kim, Kwang Mahn | - |
dc.contributor.affiliatedAuthor | Kim, Kyoung Nam | - |
dc.contributor.affiliatedAuthor | Kim, Kwang Mahn | - |
dc.citation.volume | 9 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 97 | - |
dc.identifier.bibliographicCitation | MATERIALS, Vol.9(2) : 97, 2016 | - |
dc.date.modified | 2017-02-24 | - |
dc.identifier.rimsid | 47502 | - |
dc.type.rims | ART | - |
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