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Elevated serum CA 19-9 levels in patients with pulmonary nontuberculous mycobacterial disease

DC Field Value Language
dc.contributor.author강영애-
dc.contributor.author김세규-
dc.contributor.author김송이-
dc.contributor.author김영삼-
dc.contributor.author박무석-
dc.contributor.author송주한-
dc.contributor.author장준-
dc.contributor.author정경수-
dc.date.accessioned2017-02-24T11:22:31Z-
dc.date.available2017-02-24T11:22:31Z-
dc.date.issued2016-
dc.identifier.issn1413-8670-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/146752-
dc.description.abstractIncreased serum CA 19-9 levels in patients with nonmalignant diseases have been investigated in previous reports. This study evaluates the clinical significance of serum CA 19-9 elevation in pulmonary nontuberculous mycobacterial disease and pulmonary tuberculosis. The median CA 19-9 level was higher in patients with pulmonary nontuberculous mycobacterial disease than in patients with pulmonary tuberculosis (pulmonary nontuberculous mycobacterial disease: 13.80, tuberculosis: 5.85, p<0.001). A multivariate logistic regression analysis performed in this study showed that Mycobacterium abscessus (OR 9.97, 95% CI: 1.58, 62.80; p=0.014) and active phase of pulmonary nontuberculous mycobacterial disease (OR 12.18, 95% CI: 1.07, 138.36, p=0.044) were found to be risk factors for serum CA 19-9 elevation in pulmonary nontuberculous mycobacterial disease. The serum CA 19-9 levels showed a tendency to decrease during successful treatment of pulmonary nontuberculous mycobacterial disease but not in pulmonary tuberculosis. These findings suggest that CA 19-9 may be a useful marker for monitoring therapeutic responses in pulmonary nontuberculous mycobacterial disease, although it is not pulmonary nontuberculous mycobacterial disease-specific marker.-
dc.description.statementOfResponsibilityrestriction-
dc.format.extent26~32-
dc.languageEnglish-
dc.publisherElsevier Editora-
dc.relation.isPartOfBRAZILIAN JOURNAL OF INFECTIOUS DISEASES-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHAnti-Bacterial Agents/administration & dosage-
dc.subject.MESHBiomarkers/blood-
dc.subject.MESHCA-19-9 Antigen/blood*-
dc.subject.MESHDrug Therapy, Combination-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHLung Diseases/blood*-
dc.subject.MESHLung Diseases/drug therapy-
dc.subject.MESHLung Diseases/microbiology-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMycobacterium Infections, Nontuberculous/classification*-
dc.titleElevated serum CA 19-9 levels in patients with pulmonary nontuberculous mycobacterial disease-
dc.typeArticle-
dc.publisher.locationBrazil-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Internal Medicine-
dc.contributor.googleauthorJi Young Hong-
dc.contributor.googleauthorSun Hee Jang-
dc.contributor.googleauthorSong Yee Kim-
dc.contributor.googleauthorKyung Soo Chung-
dc.contributor.googleauthorJoo Han Song-
dc.contributor.googleauthorMoo Suk Park-
dc.contributor.googleauthorYoung Sam Kim-
dc.contributor.googleauthorSe Kyu Kim-
dc.contributor.googleauthorJoon Chang-
dc.contributor.googleauthorYoung Ae Kang-
dc.identifier.doi10.1016/j.bjid.2015.09.005-
dc.contributor.localIdA00057-
dc.contributor.localIdA00602-
dc.contributor.localIdA00626-
dc.contributor.localIdA00707-
dc.contributor.localIdA01457-
dc.contributor.localIdA02062-
dc.contributor.localIdA03472-
dc.contributor.localIdA03570-
dc.relation.journalcodeJ02850-
dc.identifier.eissn1678-4391-
dc.identifier.pmid26613892-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S1413867015001944-
dc.subject.keywordBiological marker-
dc.subject.keywordCarbohydrate antigen 19-9-
dc.subject.keywordNontuberculous mycobacteria-
dc.subject.keywordTuberculosis-
dc.contributor.alternativeNameKang, Young Ae-
dc.contributor.alternativeNameKim, Se Kyu-
dc.contributor.alternativeNameKim, Song Yi-
dc.contributor.alternativeNameKim, Young Sam-
dc.contributor.alternativeNamePark, Moo Suk-
dc.contributor.alternativeNameSong, Joo Han-
dc.contributor.alternativeNameChang, Joon-
dc.contributor.alternativeNameJung, Kyung Soo-
dc.contributor.affiliatedAuthorKang, Young Ae-
dc.contributor.affiliatedAuthorKim, Se Kyu-
dc.contributor.affiliatedAuthorKim, Song Yi-
dc.contributor.affiliatedAuthorKim, Young Sam-
dc.contributor.affiliatedAuthorPark, Moo Suk-
dc.contributor.affiliatedAuthorSong, Joo Han-
dc.contributor.affiliatedAuthorChang, Joon-
dc.contributor.affiliatedAuthorJung, Kyung Soo-
dc.citation.volume20-
dc.citation.number1-
dc.citation.startPage26-
dc.citation.endPage32-
dc.identifier.bibliographicCitationBRAZILIAN JOURNAL OF INFECTIOUS DISEASES, Vol.20(1) : 26-32, 2016-
dc.date.modified2017-02-24-
dc.identifier.rimsid47495-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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