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Prosthetic graft interposition of the brachiocephalic veins or superior vena cava combined with resection of malignant tumours: Graft patency and risk factors for graft occlusion

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dc.contributor.author이근동-
dc.date.accessioned2017-02-24T11:14:22Z-
dc.date.available2017-02-24T11:14:22Z-
dc.date.issued2016-
dc.identifier.issn2072-1439-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/146704-
dc.description.abstractBACKGROUND: We aimed to assess graft patency in patients undergoing prosthetic graft interposition of the brachiocephalic veins (BCVs) or the superior vena cava (SVC) combined with resection of malignant tumours. METHODS: A retrospective analysis was conducted on 16 patients who underwent prosthetic graft interposition of the BCVs or the SVC between 1998 and 2012. RESULTS: Among a total of 20 grafts in 16 patients (unilateral graft interposition in 12, bilateral graft interposition in 4), 8 grafts were occluded in 8 patients. Overall graft patency rate was 64.6%, 42.4% at the 2- and 5-year follow-up. Graft patency rate of the left BCV was significantly lower than that of the right BCV or the SVC (2-year patency, 38.1% vs. 81.8%, P=0.024). In univariate analysis, the superior anastomosis site [left BCV vs. right BCV; hazard ratio (HR) =2.312; 95% confidence interval (CI), 1.015-5.265; P=0.046], the inferior anastomosis site (right atrial appendage vs. SVC; HR =2.409; 95% CI, 1.124-5.161; P=0.024), and interruption of warfarin (HR =5.015; 95% CI, 1.106-22.734; P=0.037) were significant risk factors for graft occlusion. Graft occlusive symptoms were identified in 4 patients who underwent unilateral graft interposition. CONCLUSIONS: Prosthetic graft interposition between the left BCV and the right atrial appendage resulted in a significant rate of graft occlusion. Prosthetic graft interposition of the bilateral BCVs and long-term warfarin therapy may be necessary to prevent graft occlusive symptoms.-
dc.description.statementOfResponsibilityopen-
dc.format.extent61~67-
dc.languageEnglish-
dc.publisherPioneer Bioscience Pub. Co.-
dc.relation.isPartOfJOURNAL OF THORACIC DISEASE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleProsthetic graft interposition of the brachiocephalic veins or superior vena cava combined with resection of malignant tumours: Graft patency and risk factors for graft occlusion-
dc.typeArticle-
dc.publisher.locationChina-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Thoracic & Cardiovascular Surgery-
dc.contributor.googleauthorGeun Dong Lee-
dc.contributor.googleauthorHyeong Ryul Kim-
dc.contributor.googleauthorSe Hoon Choi-
dc.contributor.googleauthorYong-Hee Kim-
dc.contributor.googleauthorDong Kwan Kim-
dc.contributor.googleauthorSeung-Il Park-
dc.identifier.doi10.3978/j.issn.2072-1439.2016.01.07-
dc.contributor.localIdA04621-
dc.relation.journalcodeJ01907-
dc.identifier.eissn2077-6624-
dc.identifier.pmid26904213-
dc.subject.keywordSuperior vena cava (SVC)-
dc.subject.keywordbrachiocephalic veins (BCVs)-
dc.subject.keywordgraft-
dc.subject.keywordpatency-
dc.subject.keywordreconstruction-
dc.contributor.alternativeNameLee, Geun Dong-
dc.contributor.affiliatedAuthorLee, Geun Dong-
dc.citation.volume8-
dc.citation.number1-
dc.citation.startPage61-
dc.citation.endPage67-
dc.identifier.bibliographicCitationJOURNAL OF THORACIC DISEASE, Vol.8(1) : 61-67, 2016-
dc.date.modified2017-02-24-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers

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