290 321

Cited 2 times in

Prosthetic graft interposition of the brachiocephalic veins or superior vena cava combined with resection of malignant tumours: Graft patency and risk factors for graft occlusion

Authors
 Geun Dong Lee  ;  Hyeong Ryul Kim  ;  Se Hoon Choi  ;  Yong-Hee Kim  ;  Dong Kwan Kim  ;  Seung-Il Park 
Citation
 JOURNAL OF THORACIC DISEASE, Vol.8(1) : 61-67, 2016 
Journal Title
JOURNAL OF THORACIC DISEASE
ISSN
 2072-1439 
Issue Date
2016
Keywords
Superior vena cava (SVC) ; brachiocephalic veins (BCVs) ; graft ; patency ; reconstruction
Abstract
BACKGROUND: We aimed to assess graft patency in patients undergoing prosthetic graft interposition of the brachiocephalic veins (BCVs) or the superior vena cava (SVC) combined with resection of malignant tumours.
METHODS: A retrospective analysis was conducted on 16 patients who underwent prosthetic graft interposition of the BCVs or the SVC between 1998 and 2012.
RESULTS: Among a total of 20 grafts in 16 patients (unilateral graft interposition in 12, bilateral graft interposition in 4), 8 grafts were occluded in 8 patients. Overall graft patency rate was 64.6%, 42.4% at the 2- and 5-year follow-up. Graft patency rate of the left BCV was significantly lower than that of the right BCV or the SVC (2-year patency, 38.1% vs. 81.8%, P=0.024). In univariate analysis, the superior anastomosis site [left BCV vs. right BCV; hazard ratio (HR) =2.312; 95% confidence interval (CI), 1.015-5.265; P=0.046], the inferior anastomosis site (right atrial appendage vs. SVC; HR =2.409; 95% CI, 1.124-5.161; P=0.024), and interruption of warfarin (HR =5.015; 95% CI, 1.106-22.734; P=0.037) were significant risk factors for graft occlusion. Graft occlusive symptoms were identified in 4 patients who underwent unilateral graft interposition.
CONCLUSIONS: Prosthetic graft interposition between the left BCV and the right atrial appendage resulted in a significant rate of graft occlusion. Prosthetic graft interposition of the bilateral BCVs and long-term warfarin therapy may be necessary to prevent graft occlusive symptoms.
Files in This Item:
T201601126.pdf Download
DOI
10.3978/j.issn.2072-1439.2016.01.07
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Geun Dong(이근동)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/146704
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links