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Cited 4 times in

Effect of the Prolonged Inspiratory to Expiratory Ratio on Oxygenation and Respiratory Mechanics During Surgical Procedures

DC FieldValueLanguage
dc.contributor.author김민수-
dc.contributor.author민나현-
dc.contributor.author박진하-
dc.contributor.author신서경-
dc.contributor.author이재훈-
dc.contributor.author이종석-
dc.date.accessioned2017-02-24T08:20:30Z-
dc.date.available2017-02-24T08:20:30Z-
dc.date.issued2016-
dc.identifier.issn0025-7974-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/146631-
dc.description.abstractProlonged inspiratory to expiratory (I:E) ratio ventilation has been researched to reduce lung injury and improve oxygenation in surgical patients with one-lung ventilation (OLV) or carbon dioxide (CO2) pneumoperitoneum. We aimed to confirm the efficacy of the 1:1 equal ratio ventilation (ERV) compared with the 1:2 conventional ratio ventilation (CRV) during surgical procedures. Electronic databases, including PubMed, Embase, Cochrane Central Register of Controlled Trials, Web of Science, and Google Scholar were searched.Prospective interventional trials that assessed the effects of prolonged I:E ratio of 1:1 during surgical procedures. Adult patients undergoing OLV or CO2 pneumoperitoneum as specific interventions depending on surgical procedures. The included studies were examined with the Cochrane Collaboration's tool. The data regarding intraoperative oxygenation and respiratory mechanics were extracted, and then pooled with standardized mean difference (SMD) using the method of Hedges. Seven trials (498 total patients, 274 with ERV) were included. From overall analysis, ERV did not improve oxygenation at 20 or 30 minutes after specific interventions (SMD 0.193, 95% confidence interval (CI): -0.094 to 0.481, P = 0.188). From subgroup analyses, ERV provided significantly improved oxygenation only with laparoscopy (SMD 0.425, 95% CI: 0.167-0.682, P = 0.001). At 60 minutes after the specific interventions, ERV improved oxygenation significantly in the overall analysis (SMD 0.447, 95% CI: 0.209-0.685, P < 0.001) as well as in the subgroup analyses with OLV (SMD 0.328, 95% CI: 0.011-0.644, P = 0.042) and laparoscopy (SMD 0.668, 95% CI: 0.052-1.285, P = 0.034). ERV provided lower peak airway pressure (Ppeak) and plateau airway pressure (Pplat) than CRV, regardless of the type of intervention. The relatively small number of the included articles and their heterogeneity could be the main limitations. ERV improved oxygenation at all of the assessment points during laparoscopy. In OLV, oxygenation improvement with ERV was observed 1 hour after application. ERV could be beneficial to reduce the Ppeak and Pplat.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherLippincott Williams & Wilkins-
dc.relation.isPartOfMEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHHumans-
dc.subject.MESHProspective Studies-
dc.subject.MESHRespiration, Artificial/methods*-
dc.subject.MESHRespiratory Mechanics*-
dc.subject.MESHSurgical Procedures, Operative/methods*-
dc.titleEffect of the Prolonged Inspiratory to Expiratory Ratio on Oxygenation and Respiratory Mechanics During Surgical Procedures-
dc.typeArticle-
dc.publisher.locationUnited States-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Anesthesiology and Pain Medicine-
dc.contributor.googleauthorJin Ha Park-
dc.contributor.googleauthorJong Seok Lee-
dc.contributor.googleauthorJae Hoon Lee-
dc.contributor.googleauthorSeokyung Shin-
dc.contributor.googleauthorNar Hyun Min-
dc.contributor.googleauthorMin-Soo Kim-
dc.identifier.doi10.1097/MD.0000000000003269-
dc.contributor.localIdA00463-
dc.contributor.localIdA04565-
dc.contributor.localIdA01704-
dc.contributor.localIdA02109-
dc.contributor.localIdA03092-
dc.contributor.localIdA03141-
dc.relation.journalcodeJ02214-
dc.identifier.eissn1536-5964-
dc.identifier.pmid27043700-
dc.contributor.alternativeNameKim, Min Soo-
dc.contributor.alternativeNameMin, Nar Hyun-
dc.contributor.alternativeNamePark, Jin Ha-
dc.contributor.alternativeNameShin, Seo Kyung-
dc.contributor.alternativeNameLee, Jae Hoon-
dc.contributor.alternativeNameLee, Jong Seok-
dc.contributor.affiliatedAuthorKim, Min Soo-
dc.contributor.affiliatedAuthorMin, Nar Hyun-
dc.contributor.affiliatedAuthorPark, Jin Ha-
dc.contributor.affiliatedAuthorShin, Seo Kyung-
dc.contributor.affiliatedAuthorLee, Jae Hoon-
dc.contributor.affiliatedAuthorLee, Jong Seok-
dc.citation.volume95-
dc.citation.number13-
dc.citation.startPage3269-
dc.identifier.bibliographicCitationMEDICINE, Vol.95(13) : 3269, 2016-
dc.date.modified2017-02-24-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers

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