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Genetic analysis of ovarian microcystic stromal tumor
DC Field | Value | Language |
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dc.contributor.author | 김상운 | - |
dc.contributor.author | 김성훈 | - |
dc.contributor.author | 김영태 | - |
dc.contributor.author | 김현수 | - |
dc.contributor.author | 남은지 | - |
dc.contributor.author | 이재훈 | - |
dc.contributor.author | 이정윤 | - |
dc.contributor.author | 조남훈 | - |
dc.date.accessioned | 2017-02-24T07:44:26Z | - |
dc.date.available | 2017-02-24T07:44:26Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 2287-8572 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/146510 | - |
dc.description.abstract | Microcystic stromal tumor (MCST) of the ovary is a rare subtype of ovarian tumor first described in 2009. Although high nuclear expression of β-catenin and β-catenin gene (CTNNB1) mutation are related with ovarian MCST, the origin and genetic background of ovarian MCST remain unclear. In this study, two cases of ovarian MCST are presented. Microscopically, the tumors showed a microcystic pattern and regions with lobulated cellular masses with intervening hyalinized, fibrous stroma. Tumor cells of both cases were stained with CD10, vimentin, and Wilms tumor 1. Genetic analysis was performed and β-catenin gene (CTNNB1) mutation in exon 3 was detected in both cases. This is the first report in regards of detecting CTNNB1 mutation in ovarian MCST through the use of pyrosequencing (a novel sequencing technique). | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 157~162 | - |
dc.language | English | - |
dc.publisher | Korean Society of Obstetrics and Gynecology | - |
dc.relation.isPartOf | Obstetrics & Gynecology Science | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Genetic analysis of ovarian microcystic stromal tumor | - |
dc.type | Article | - |
dc.publisher.location | Korea (South) | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Obstetrics & Gynecology | - |
dc.contributor.googleauthor | Jae Hoon Lee | - |
dc.contributor.googleauthor | Hyun-Soo Kim | - |
dc.contributor.googleauthor | Nam Hoon Cho | - |
dc.contributor.googleauthor | Jung-Yun Lee | - |
dc.contributor.googleauthor | Sunghoon Kim | - |
dc.contributor.googleauthor | Sang Wun Kim | - |
dc.contributor.googleauthor | Young Tae Kim | - |
dc.contributor.googleauthor | Eun Ji Nam | - |
dc.identifier.doi | 10.5468/ogs.2016.59.2.157 | - |
dc.contributor.localId | A00526 | - |
dc.contributor.localId | A00595 | - |
dc.contributor.localId | A00729 | - |
dc.contributor.localId | A01114 | - |
dc.contributor.localId | A01262 | - |
dc.contributor.localId | A04636 | - |
dc.contributor.localId | A04638 | - |
dc.contributor.localId | A03812 | - |
dc.relation.journalcode | J02408 | - |
dc.relation.journalsince | 2013~ | - |
dc.identifier.pmid | 27004209 | - |
dc.relation.journalbefore | ~2012 Korean Journal of Obstetrics and Gynecology | - |
dc.subject.keyword | CTNNB1 mutation | - |
dc.subject.keyword | Microcystic stromal tumor | - |
dc.subject.keyword | Ovary | - |
dc.subject.keyword | Pyrosequencing | - |
dc.contributor.alternativeName | Kim, Sang Wun | - |
dc.contributor.alternativeName | Kim, Sung Hoon | - |
dc.contributor.alternativeName | Kim, Young Tae | - |
dc.contributor.alternativeName | Kim, Hyun-Soo | - |
dc.contributor.alternativeName | Nam, Eun Ji | - |
dc.contributor.alternativeName | Lee, Jae Hoon | - |
dc.contributor.alternativeName | Lee, Jung-Yun | - |
dc.contributor.alternativeName | Cho, Nam Hoon | - |
dc.contributor.affiliatedAuthor | Kim, Sang Wun | - |
dc.contributor.affiliatedAuthor | Kim, Sung Hoon | - |
dc.contributor.affiliatedAuthor | Kim, Young Tae | - |
dc.contributor.affiliatedAuthor | Kim, Hyun-Soo | - |
dc.contributor.affiliatedAuthor | Nam, Eun Ji | - |
dc.contributor.affiliatedAuthor | Lee, Jae Hoon | - |
dc.contributor.affiliatedAuthor | Lee, Jung-Yun | - |
dc.contributor.affiliatedAuthor | Cho, Nam Hoon | - |
dc.citation.volume | 59 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 157 | - |
dc.citation.endPage | 162 | - |
dc.identifier.bibliographicCitation | Obstetrics & Gynecology Science, Vol.59(2) : 157-162, 2016 | - |
dc.date.modified | 2017-02-24 | - |
dc.identifier.rimsid | 45142 | - |
dc.type.rims | ART | - |
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