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The effects of chlorhexidine gluconate bathing on health care-associated infection in intensive care units: A meta-analysis

DC Field Value Language
dc.contributor.author김정민-
dc.contributor.author김하연-
dc.contributor.author나성원-
dc.contributor.author신증수-
dc.contributor.author이우경-
dc.date.accessioned2017-02-24T07:35:51Z-
dc.date.available2017-02-24T07:35:51Z-
dc.date.issued2016-
dc.identifier.issn0883-9441-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/146464-
dc.description.abstractPURPOSE: The purpose was to assess the effects of chlorhexidine gluconate (CHG) bathing on health care-associated infections among critically ill patients. METHODS: This meta-analysis evaluated English-language studies from the PubMed, Embase, and Cochrane databases. The Cochrane Collaboration methodology was used to evaluate all publications regarding daily CHG bathing and the risks of acquiring central line-associated bloodstream infection (CLABSI), methicillin-resistant Staphylococcus aureus (MRSA), and vancomycin-resistant Enterococcus (VRE). Risk ratios (RRs) and the ratio of the log RRs (RRR) were estimated with 95% confidence intervals (CIs). RESULTS: Eighteen studies were included. Compared with conventional care, the RRs (95% CIs) for CLABSI, MRSA, and VRE with CHG bathing were 0.45 (0.37-0.55), 0.67 (0.59-0.77), and 0.60 (0.42-0.85), respectively (all, P < .05). For MRSA acquisition, CHG bathing with concomitant nasal antibiotics provided a lower incidence compared with only CHG bathing (RRR: 0.81, 95% CI: 0.66-0.98, P = .035). Greater risk reduction was also observed in studies with prolonged interventions (RRR per 1-month extension: -0.02, P = .027). CONCLUSIONS: Daily CHG bathing was associated with reduced risks of acquiring CLABSI, MRSA, and VRE. A prolonged intervention period and concomitant nasal antibiotic use were associated with lower risks of MRSA acquisition.-
dc.description.statementOfResponsibilityrestriction-
dc.format.extent126~137-
dc.languageEnglish-
dc.publisherW.B. Saunders-
dc.relation.isPartOfJOURNAL OF CRITICAL CARE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHBaths*-
dc.subject.MESHCatheter-Related Infections/prevention & control-
dc.subject.MESHChlorhexidine/administration & dosage-
dc.subject.MESHChlorhexidine/analogs & derivatives*-
dc.subject.MESHCross Infection/epidemiology-
dc.subject.MESHCross Infection/prevention & control*-
dc.subject.MESHDisinfectants/administration & dosage*-
dc.subject.MESHGram-Positive Bacterial Infections/prevention & control-
dc.subject.MESHHumans-
dc.subject.MESHIntensive Care Units/statistics & numerical data*-
dc.subject.MESHMethicillin-Resistant Staphylococcus aureus-
dc.titleThe effects of chlorhexidine gluconate bathing on health care-associated infection in intensive care units: A meta-analysis-
dc.typeArticle-
dc.publisher.locationUnited States-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Anesthesiology and Pain Medicine-
dc.contributor.googleauthorHa Yeon Kim-
dc.contributor.googleauthorWoo Kyung Lee-
dc.contributor.googleauthorSungwon Na-
dc.contributor.googleauthorYun Ho Roh-
dc.contributor.googleauthorCheung Soo Shin-
dc.contributor.googleauthorJeongmin Kim-
dc.identifier.doi10.1016/j.jcrc.2015.11.011-
dc.contributor.localIdA00884-
dc.contributor.localIdA04550-
dc.contributor.localIdA01232-
dc.contributor.localIdA02159-
dc.contributor.localIdA02990-
dc.relation.journalcodeJ01358-
dc.identifier.eissn1557-8615-
dc.identifier.pmid26705765-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0883944115005626-
dc.subject.keywordChlorhexidine bathing-
dc.subject.keywordHealth care–associated infection-
dc.subject.keywordMeta-analysis-
dc.subject.keywordRisk ratio-
dc.contributor.alternativeNameKim, Jeongmin-
dc.contributor.alternativeNameKim, Ha Yan-
dc.contributor.alternativeNameNa, Sung Won-
dc.contributor.alternativeNameShin, Cheung Soo-
dc.contributor.alternativeNameLee, Woo Kyung-
dc.contributor.affiliatedAuthorKim, Jeongmin-
dc.contributor.affiliatedAuthorKim, Ha Yan-
dc.contributor.affiliatedAuthorNa, Sung Won-
dc.contributor.affiliatedAuthorShin, Cheung Soo-
dc.contributor.affiliatedAuthorLee, Woo Kyung-
dc.citation.volume32-
dc.citation.startPage126-
dc.citation.endPage137-
dc.identifier.bibliographicCitationJOURNAL OF CRITICAL CARE, Vol.32 : 126-137, 2016-
dc.date.modified2017-02-24-
dc.identifier.rimsid45108-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers

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