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Change of Nutritional Status Assessed Using Subjective Global Assessment Is Associated With All-Cause Mortality in Incident Dialysis Patients

DC FieldValueLanguage
dc.contributor.author강신욱-
dc.contributor.author권영은-
dc.contributor.author기연경-
dc.contributor.author박정탁-
dc.contributor.author유태현-
dc.contributor.author윤창연-
dc.contributor.author한승규-
dc.contributor.author한승혁-
dc.contributor.author한인미-
dc.date.accessioned2017-02-24T03:46:18Z-
dc.date.available2017-02-24T03:46:18Z-
dc.date.issued2016-
dc.identifier.issn0025-7974-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/146436-
dc.description.abstractSubjective global assessment (SGA) is associated with mortality in end-stage renal disease (ESRD) patients. However, little is known whether improvement or deterioration of nutritional status after dialysis initiation influences the clinical outcome. We aimed to elucidate the association between changes in nutritional status determined by SGA during the first year of dialysis and all-cause mortality in incident ESRD patients. This was a multicenter, prospective cohort study. Incident dialysis patients with available SGA data at both baseline and 12 months after dialysis commencement (n = 914) were analyzed. Nutritional status was defined as well nourished (WN, SGA A) or malnourished (MN, SGA B or C). The patients were divided into 4 groups according to the change in nutritional status between baseline and 12 months after dialysis commencement: group 1, WN to WN; group 2, MN to WN; group 3, WN to MN; and group 4, MN to MN. Cox proportional hazard analysis was performed to clarify the association between changes in nutritional status and mortality. Being in the MN group at 12 months after dialysis initiation, but not at baseline, was a significant risk factor for mortality. There was a significant difference in the 3-year survival rates among the groups (group 1, 92.2%; group 2, 86.0%; group 3, 78.2%; and group 4, 63.5%; log-rank test, P < 0.001). Multivariate Cox regression analysis revealed that the mortality risk was significantly higher in group 3 than in group 1 (hazard ratio [HR] 2.77, 95% confidence interval [CI] 1.27-6.03, P = 0.01) whereas the mortality risk was significantly lower in group 2 compared with group 4 (HR 0.35, 95% CI 0.17-0.71, P < 0.01) even after adjustment for confounding factors. Moreover, mortality risk of group 3 was significantly higher than in group 2 (HR 2.89, 95% CI 1.22-6.81, P = 0.02); there was no significant difference between groups 1 and 2. The changes in nutritional status assessed by SGA during the first year of dialysis were associated with all-cause mortality in incident ESRD patients.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherLippincott Williams & Wilkins-
dc.relation.isPartOfMEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAge Factors-
dc.subject.MESHAged-
dc.subject.MESHBiomarkers-
dc.subject.MESHBody Mass Index-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHKidney Failure, Chronic/mortality*-
dc.subject.MESHKidney Failure, Chronic/therapy*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNutrition Assessment*-
dc.subject.MESHNutritional Status*-
dc.subject.MESHProportional Hazards Models-
dc.subject.MESHProspective Studies-
dc.subject.MESHProtein-Energy Malnutrition/mortality-
dc.subject.MESHRegression Analysis-
dc.subject.MESHRenal Dialysis/statistics & numerical data*-
dc.subject.MESHRisk Factors-
dc.subject.MESHSex Factors-
dc.subject.MESHSurvival Analysis-
dc.titleChange of Nutritional Status Assessed Using Subjective Global Assessment Is Associated With All-Cause Mortality in Incident Dialysis Patients-
dc.typeArticle-
dc.publisher.locationUnited States-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Internal Medicine-
dc.contributor.googleauthorYoung Eun Kwon-
dc.contributor.googleauthorYoun Kyung Kee-
dc.contributor.googleauthorChang-Yun Yoon-
dc.contributor.googleauthorIn Mee Han-
dc.contributor.googleauthorSeung Gyu Han-
dc.contributor.googleauthorKyoung Sook Park-
dc.contributor.googleauthorMi Jung Lee-
dc.contributor.googleauthorJung Tak Park-
dc.contributor.googleauthorSeung H. Han-
dc.contributor.googleauthorTae-Hyun Yoo-
dc.contributor.googleauthorYong-Lim Kim-
dc.contributor.googleauthorYon Su Kim-
dc.contributor.googleauthorChul Woo Yang-
dc.contributor.googleauthorNam-Ho Kim-
dc.contributor.googleauthorShin-Wook Kang-
dc.identifier.doi10.1097/MD.0000000000002714-
dc.contributor.localIdA00053-
dc.contributor.localIdA00232-
dc.contributor.localIdA00276-
dc.contributor.localIdA01654-
dc.contributor.localIdA02526-
dc.contributor.localIdA02613-
dc.contributor.localIdA04298-
dc.contributor.localIdA04304-
dc.contributor.localIdA04315-
dc.relation.journalcodeJ02214-
dc.identifier.eissn1536-5964-
dc.identifier.pmid26886609-
dc.contributor.alternativeNameKang, Shin Wook-
dc.contributor.alternativeNameKwon, Young Eun-
dc.contributor.alternativeNameKee, Youn Kyung-
dc.contributor.alternativeNamePark, Jung Tak-
dc.contributor.alternativeNameYoo, Tae Hyun-
dc.contributor.alternativeNameYoon, Chang Yun-
dc.contributor.alternativeNameHan, Seung Gyu-
dc.contributor.alternativeNameHan, Seung Hyeok-
dc.contributor.alternativeNameHan, In Mee-
dc.contributor.affiliatedAuthorKang, Shin Wook-
dc.contributor.affiliatedAuthorKwon, Young Eun-
dc.contributor.affiliatedAuthorKee, Youn Kyung-
dc.contributor.affiliatedAuthorPark, Jung Tak-
dc.contributor.affiliatedAuthorYoo, Tae Hyun-
dc.contributor.affiliatedAuthorYoon, Chang Yun-
dc.contributor.affiliatedAuthorHan, Seung Gyu-
dc.contributor.affiliatedAuthorHan, Seung Hyeok-
dc.contributor.affiliatedAuthorHan, In Mee-
dc.citation.volume95-
dc.citation.number7-
dc.citation.startPage2714-
dc.identifier.bibliographicCitationMEDICINE, Vol.95(7) : 2714, 2016-
dc.date.modified2017-02-24-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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