Cited 51 times in
Use of TachoSil® patches to prevent pancreatic leaks after distal pancreatectomy: a prospective, multicenter, randomized controlled study
DC Field | Value | Language |
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dc.contributor.author | 강창무 | - |
dc.contributor.author | 박준성 | - |
dc.contributor.author | 윤동섭 | - |
dc.contributor.author | 이우정 | - |
dc.contributor.author | 황호경 | - |
dc.contributor.author | 김재근 | - |
dc.date.accessioned | 2017-02-24T03:25:35Z | - |
dc.date.available | 2017-02-24T03:25:35Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 1868-6974 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/146341 | - |
dc.description.abstract | BACKGROUND: We performed a prospective, multicenter, randomized controlled study to investigate the clinical outcomes, including postoperative pancreatic fistulas (POPF), after using the TachoSil® patch in distal pancreatectomy (NCT01550406). METHODS: Between June 2012 and September 2014, 101 patients at five centers were randomized into Control (n = 53) and TachoSil (n = 48) groups. In all patients, the pancreas was resected using a stapler with Endo-GIA™ staples. The TachoSil patch was wrapped around the pancreatic stump only in the TachoSil group, not in Control group. RESULTS: The patient characteristics, including age and diagnosis, were comparable in both groups. The mean operation time (159.4 vs. 172.3 min, P = 0.081) and postoperative hospital stay (10.0 vs. 9.7 days, P = 0.279) were similar in the Control and TachoSil groups, respectively. The overall incidence of POPF was 62.4% (n = 63). The distribution of grades A, B, and C POPF was similar in the Control (n = 14/14/1) and TachoSil (n = 23/11/0) groups, as were the overall incidence (54.7% vs. 70.8%, P = 0.095) and the incidence of grade B and C POPF (28.3% vs. 22.9%, P = 0.536). CONCLUSION: This study showed that the TachoSil® patch did not reduce the incidence of POPF after distal pancreatectomy. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.format.extent | 110~117 | - |
dc.language | English | - |
dc.publisher | Wiley Japan | - |
dc.relation.isPartOf | JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Drug Combinations | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Fibrinogen/therapeutic use* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Length of Stay | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Operative Time | - |
dc.subject.MESH | Pancreas/anatomy & histology | - |
dc.subject.MESH | Pancreatectomy* | - |
dc.subject.MESH | Pancreatic Fistula/etiology | - |
dc.subject.MESH | Pancreatic Fistula/prevention & control | - |
dc.subject.MESH | Postoperative Complications/prevention & control* | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Thrombin/therapeutic use* | - |
dc.subject.MESH | Young Adult | - |
dc.title | Use of TachoSil® patches to prevent pancreatic leaks after distal pancreatectomy: a prospective, multicenter, randomized controlled study | - |
dc.type | Article | - |
dc.publisher.location | Japan | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Surgery | - |
dc.contributor.googleauthor | Joon Seong Park | - |
dc.contributor.googleauthor | Doo-ho Lee | - |
dc.contributor.googleauthor | Jin-Young Jang | - |
dc.contributor.googleauthor | Youngmin Han | - |
dc.contributor.googleauthor | Dong Sup Yoon | - |
dc.contributor.googleauthor | Jae Keun Kim | - |
dc.contributor.googleauthor | Ho-Seong Han | - |
dc.contributor.googleauthor | YooSeok Yoon | - |
dc.contributor.googleauthor | DaeWook Hwang | - |
dc.contributor.googleauthor | Chang Moo Kang | - |
dc.contributor.googleauthor | Ho Kyoung Hwang | - |
dc.contributor.googleauthor | Woo Jung Lee | - |
dc.contributor.googleauthor | JinSeok Heo | - |
dc.contributor.googleauthor | Ye Rim Chang | - |
dc.contributor.googleauthor | Mee Joo Kang | - |
dc.contributor.googleauthor | Yong Chan Shin | - |
dc.contributor.googleauthor | Jihoon Chang | - |
dc.contributor.googleauthor | Hongbeom Kim | - |
dc.contributor.googleauthor | Woohyun Jung | - |
dc.contributor.googleauthor | Sun-Whe Kim | - |
dc.identifier.doi | 10.1002/jhbp.310 | - |
dc.contributor.localId | A00088 | - |
dc.contributor.localId | A01672 | - |
dc.contributor.localId | A02548 | - |
dc.contributor.localId | A02993 | - |
dc.contributor.localId | A04497 | - |
dc.contributor.localId | A00857 | - |
dc.relation.journalcode | J01440 | - |
dc.identifier.eissn | 1868-6982 | - |
dc.identifier.pmid | 26681272 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1002/jhbp.310/abstract | - |
dc.subject.keyword | Distal pancreatectomy | - |
dc.subject.keyword | Postoperative pancreatic fistula | - |
dc.subject.keyword | Prevention | - |
dc.contributor.alternativeName | Kang, Chang Moo | - |
dc.contributor.alternativeName | Park, Joon Seong | - |
dc.contributor.alternativeName | Yoon, Dong Sup | - |
dc.contributor.alternativeName | Lee, Woo Jung | - |
dc.contributor.alternativeName | Hwang, Ho Kyoung | - |
dc.contributor.alternativeName | Kim, Jae Keun | - |
dc.contributor.affiliatedAuthor | Kang, Chang Moo | - |
dc.contributor.affiliatedAuthor | Park, Joon Seong | - |
dc.contributor.affiliatedAuthor | Yoon, Dong Sup | - |
dc.contributor.affiliatedAuthor | Lee, Woo Jung | - |
dc.contributor.affiliatedAuthor | Hwang, Ho Kyoung | - |
dc.contributor.affiliatedAuthor | Kim, Jae Keun | - |
dc.citation.volume | 23 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 110 | - |
dc.citation.endPage | 117 | - |
dc.identifier.bibliographicCitation | JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES, Vol.23(2) : 110-117, 2016 | - |
dc.date.modified | 2017-02-24 | - |
dc.identifier.rimsid | 47850 | - |
dc.type.rims | ART | - |
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