Cited 17 times in
Comparison of Six Automated Treponema-Specific Antibody Assays
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김현숙 | - |
dc.contributor.author | 박금보래 | - |
dc.contributor.author | 임정훈 | - |
dc.contributor.author | 윤지훈 | - |
dc.date.accessioned | 2017-02-24T03:07:09Z | - |
dc.date.available | 2017-02-24T03:07:09Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 0095-1137 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/146247 | - |
dc.description.abstract | Six different Treponema (TP)-specific immunoassays were compared to the fluorescent treponemal antibody absorption (FTA-ABS) test. A total of 615 samples were tested. The overall percent agreement, analytical sensitivity, and analytical specificity of each assay compared to the FTA-ABS test were as follows: Architect Syphilis TP, 99.2%, 96.8%, and 100%; Cobas Syphilis, 99.8%, 99.4%, and 100%; ADVIA Centaur Syphilis, 99.8%, 99.4%, and 100%; HISCL Anti-TP assay kit, 99.7%, 98.7%, and 100%; Immunoticles Auto3 TP, 99.0%, 97.5%, and 99.6%; Mediace TPLA, 98.0%, 98.1%, and 98.0%. All results that were discrepant between the TP-specific assays were associated with samples from noninfectious cases (11 immunoassay false positives and 7 from previous syphilis cases). Our study demonstrated that TP-specific immunoassays generally showed high sensitivities, specificities, and percentages of agreement compared to FTA-ABS, with rare cases of false-positive or false-negative results. Therefore, most TP-specific immunoassays are acceptable for use in screening for syphilis. However, it is important to perform a thorough review of a patient's clinical and treatment history for interpreting the results of syphilis serology. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | American Society for Microbiology | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL MICROBIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Antibodies, Bacterial/analysis* | - |
dc.subject.MESH | Automation, Laboratory/methods* | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | Clinical Laboratory Techniques/methods* | - |
dc.subject.MESH | Diagnostic Tests, Routine/methods* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Immunoassay/methods* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Mass Screening/methods | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.subject.MESH | Syphilis/diagnosis* | - |
dc.subject.MESH | Treponema/immunology* | - |
dc.subject.MESH | Young Adult | - |
dc.title | Comparison of Six Automated Treponema-Specific Antibody Assays | - |
dc.type | Article | - |
dc.publisher.location | United States | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Laboratory Medicine | - |
dc.contributor.googleauthor | Borae G. Park | - |
dc.contributor.googleauthor | Jihoon G. Yoon | - |
dc.contributor.googleauthor | John Hoon Rim | - |
dc.contributor.googleauthor | Anna Lee | - |
dc.contributor.googleauthor | Hyon-Suk Kim | - |
dc.identifier.doi | 10.1128/JCM.02593-15 | - |
dc.contributor.localId | A01117 | - |
dc.contributor.localId | A01445 | - |
dc.contributor.localId | A04654 | - |
dc.relation.journalcode | J01325 | - |
dc.identifier.eissn | 1098-660X | - |
dc.identifier.pmid | 26560543 | - |
dc.contributor.alternativeName | Kim, Hyon Suk | - |
dc.contributor.alternativeName | Park, Borae G | - |
dc.contributor.alternativeName | Rim, John Hoon | - |
dc.contributor.affiliatedAuthor | Kim, Hyon Suk | - |
dc.contributor.affiliatedAuthor | Park, Borae G | - |
dc.contributor.affiliatedAuthor | Rim, John Hoon | - |
dc.citation.volume | 54 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 163 | - |
dc.citation.endPage | 167 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL MICROBIOLOGY, Vol.54(1) : 163-167, 2016 | - |
dc.date.modified | 2017-02-24 | - |
dc.identifier.rimsid | 51267 | - |
dc.type.rims | ART | - |
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