0 324

Cited 33 times in

Ictal electrocorticographic findings related with surgical outcomes in nonlesional neocortical epilepsy

DC FieldValueLanguage
dc.contributor.author이병인-
dc.contributor.author장진우-
dc.contributor.author허경-
dc.date.accessioned2016-05-16T11:19:51Z-
dc.date.available2016-05-16T11:19:51Z-
dc.date.issued2002-
dc.identifier.issn0920-1211-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/144312-
dc.description.abstractPurpose: To characterize ictal electrocorticographic features related to surgical outcomes in nonlesional neocortical epilepsy (NE). Methods: We analyzed 187 ictal electrocorticograms (ECoG) obtained from 18 patients who had undergone presurgical evaluation and subsequent neocortical resections (frontal: seven, parietal: one, occipital: four, multilobar: six). None of them had any MRI-detectable lesions. Various ECoG data sets recorded from eight patients who achieved a favorable surgical outcome (either seizure free or more than 90% reduction of seizure frequencies) were compared with that from ten patients with unfavorable outcome (less than 90% reduction of seizure frequencies) (follow up duration: 47±11 months). Results: Reproducible ictal onset zone (IOZ) in recurrent seizures (P=0.013) and persistent ictal discharges in IOZ from the onset to the end of seizure (P=0.004) were found more frequently in the patients with good outcome. Ictal onset patterns consisting of low voltage fast or high amplitude beta spikes predicted a good surgical outcome while rhythmic sinusoidal activity or rhythmic spike/sharp waves of slow frequency were predictive of poor outcome (P=0.01). The ictal onset rhythm consisting of gamma or beta frequencies was more prevalent in the favorable group (P=0.015). Conclusions: The presence of stable ictal circuit suggested by the consistent earliest activation of specific electrodes in the repetitive seizures (reproducible IOZ) and the active participation of IOZ throughout the attack were valuable prognostic factors in addition to the morphology and frequency of ictal onset rhythm.-
dc.description.statementOfResponsibilityopen-
dc.format.extent199~206-
dc.relation.isPartOfEPILEPSY RESEARCH-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdolescent-
dc.subject.MESHAdult-
dc.subject.MESHChild-
dc.subject.MESHElectroencephalography/statistics & numerical data*-
dc.subject.MESHEpilepsy/diagnosis-
dc.subject.MESHEpilepsy/physiopathology-
dc.subject.MESHEpilepsy/surgery*-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHNeocortex/physiopathology-
dc.subject.MESHNeocortex/surgery*-
dc.subject.MESHTreatment Outcome-
dc.titleIctal electrocorticographic findings related with surgical outcomes in nonlesional neocortical epilepsy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Neurology (신경과학)-
dc.contributor.googleauthorS.A. Park-
dc.contributor.googleauthorS.R. Lim-
dc.contributor.googleauthorG.S. Kim-
dc.contributor.googleauthorK. Heo-
dc.contributor.googleauthorS.C. Park-
dc.contributor.googleauthorJ.W. Chang-
dc.contributor.googleauthorS.S. Chung-
dc.contributor.googleauthorJ.U. Choi-
dc.contributor.googleauthorT.S. Kim-
dc.contributor.googleauthorByung In Lee-
dc.identifier.doi10.1016/S0920-1211(02)00006-2-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02797-
dc.contributor.localIdA03484-
dc.contributor.localIdA04341-
dc.relation.journalcodeJ00796-
dc.identifier.eissn1872-6844-
dc.identifier.pmid11904238-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0920121102000062#-
dc.subject.keywordIctal EEG-
dc.subject.keywordElectrocorticogram-
dc.subject.keywordEpilepsy surgery-
dc.subject.keywordOutcomeNeocortical epilepsy-
dc.contributor.alternativeNameLee, Byung In-
dc.contributor.alternativeNameChang, Jin Woo-
dc.contributor.alternativeNameHeo, Kyoung-
dc.contributor.affiliatedAuthorLee, Byung In-
dc.contributor.affiliatedAuthorChang, Jin Woo-
dc.contributor.affiliatedAuthorHeo, Kyoung-
dc.rights.accessRightsnot free-
dc.citation.volume48-
dc.citation.number3-
dc.citation.startPage199-
dc.citation.endPage206-
dc.identifier.bibliographicCitationEPILEPSY RESEARCH, Vol.48(3) : 199-206, 2002-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.