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Amoxicillin-Sulbactam (Sultamox)의 주요 임상 분리세균에 대한 시험관내 항균력

DC FieldValueLanguage
dc.contributor.author용동은-
dc.contributor.author이경원-
dc.date.accessioned2016-05-16T11:16:15Z-
dc.date.available2016-05-16T11:16:15Z-
dc.date.issued2002-
dc.identifier.issn1225-7850-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/144174-
dc.description.abstractBackground : Q-lactam antibiotics are one of the most frequently used antimicrobial agents. However, with the increase of a-lactamase-producing bacteria, penicillins and amoxicillin have become less useful. Amoxici Ili n-sulbactam (AXS) was developed to restore the activity. The aim of this study was to determine the in vitro activities of AXS against recent clinical isolates. Methods : Various aerobic bacteria tested were isolated from clinical specimens in Severance Hospital during . 2000 to 2001 Antimicrobial susceptibility was determined by the NCCLS agar dilution method. Results : Oxacillin-susceptible Staphylococcus aureus and coagulase-negative Staphylococcus I Streptococcus pneumoniae and S. pyogenes were susceptible to ampicillin-sulbactam (APS), amoxicillin-clavulanic acid (AXC) and AXS. For Moraxella (Branhamella) catarrhalis and Haemophilus influenzae, MIC9os of APS, AXC and AXS were 0.5 ug/"mL and´ 8 ug/mL, respectively, which were 16-fold lower than those of amoxicillin. For Klebsiella oxytoca and Proteus mirabilis, MIC90 of amoxicillin was >128 Pg/mL, but M1Cgos of APS, AXC and AXS were 8-32 ug/mL and 4-16 ug/mL, respectively. Conclusion : AXS showed good antimicrobial activities against oxacilli n- susceptible Staphylococcus, M. (B.) catarrhalis, H. influenzae, K oxytoca, and P. mirabilis. Therefore, It would be useful for the treatment of infections due to these organisms.-
dc.description.statementOfResponsibilityopen-
dc.format.extent203~212-
dc.relation.isPartOfJournal of the Korean Society for Chemotherapy (대한화학요법학회지)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleAmoxicillin-Sulbactam (Sultamox)의 주요 임상 분리세균에 대한 시험관내 항균력-
dc.title.alternativeIn Vitro Activities of Amoxicillin-Sulbactam (Sultamox) against Major Clinical Isolates of Bacteria-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학)-
dc.contributor.googleauthor염종화-
dc.contributor.googleauthor용동은-
dc.contributor.googleauthor김명숙-
dc.contributor.googleauthor이경원-
dc.contributor.googleauthor정윤섭-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02423-
dc.contributor.localIdA02649-
dc.relation.journalcodeJ01850-
dc.contributor.alternativeNameYong, Dong Eun-
dc.contributor.alternativeNameLee, Kyung Won-
dc.contributor.affiliatedAuthorYong, Dong Eun-
dc.contributor.affiliatedAuthorLee, Kyung Won-
dc.rights.accessRightsfree-
dc.citation.volume20-
dc.citation.number3-
dc.citation.startPage203-
dc.citation.endPage212-
dc.identifier.bibliographicCitationJournal of the Korean Society for Chemotherapy (대한화학요법학회지), Vol.20(3) : 203-212, 2002-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers

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