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화학발광자동면역분석기 Vitros ECi®를 이용한 TSH, Free Triiodothyronine, Free Thyroxine 및 Estradiol 검사 평가

DC FieldValueLanguage
dc.contributor.author김정호-
dc.contributor.author용동은-
dc.date.accessioned2016-05-16T11:11:27Z-
dc.date.available2016-05-16T11:11:27Z-
dc.date.issued2002-
dc.identifier.issn1598-6535-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/143993-
dc.description.abstractBackground: The analytical performance of the Vitros ECi® Immunodiagnostic System on the thyroid stimulating hormone (TSH), free triiodothyronine (FT3), free thyroxine (FT4) and estradiol (E2) assays, which are based on electrochemical luminescence to replace the radioimmunoassay was evaluated. Methods: The precision as measured by the NCCLS protocol and a comparison of the method were done for each TSH, FT3, FT4, and E2 assay. The functional sensitivity and linearity tests were performed for both TSH and E2. The free hormone validity test was performed for both the FT3 and FT4. Results: All four analytes showed an acceptable precision. The functional sensitivities of TSH and E2 were 0.007 ㎖μ/ℓ, and 87 p㏖/ℓ, respectively. TSH and E2 showed excellent linearity up to 78 ㎖μ/㎖, and up to 7,700 p㏖/ℓ, respectively. The free hormone validity test showed acceptable results demonstrating accurate free hormone determination. The E2 showed a significant proportional bias requiring an adjustment of the reference range, However, the other analytes showed good agreement with a slight proportional bias. Conclusions: The TSH, FT3, FT4, and E2 assay by Vitros ECi® exhibited excellent performance overcoming the drawbacks of a conventional radioimmunoassay.-
dc.description.statementOfResponsibilityopen-
dc.format.extent95~100-
dc.relation.isPartOfKorean Journal of Clinical Pathology (대한임상병리학회지)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.title화학발광자동면역분석기 Vitros ECi®를 이용한 TSH, Free Triiodothyronine, Free Thyroxine 및 Estradiol 검사 평가-
dc.title.alternativeEvaluation of the TSH, Free Triiodothyronine, Free Thyroxine and Estradiol Test of the Vitros ECi® Immunodiagnostic System-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학)-
dc.contributor.googleauthor용동은-
dc.contributor.googleauthor선영규-
dc.contributor.googleauthor이건수-
dc.contributor.googleauthor김정호-
dc.contributor.googleauthor권오헌-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00903-
dc.contributor.localIdA02423-
dc.relation.journalcodeJ01988-
dc.subject.keywordChemiluminescence immunoassay-
dc.subject.keywordTSH-
dc.subject.keywordFree triiodothyronine-
dc.subject.keywordFree thyroxine-
dc.subject.keywordEstradiol-
dc.contributor.alternativeNameKim, Jeong Ho-
dc.contributor.alternativeNameYong, Dong Eun-
dc.contributor.affiliatedAuthorKim, Jeong Ho-
dc.contributor.affiliatedAuthorYong, Dong Eun-
dc.rights.accessRightsfree-
dc.citation.volume22-
dc.citation.number2-
dc.citation.startPage95-
dc.citation.endPage100-
dc.identifier.bibliographicCitationKorean Journal of Clinical Pathology (대한임상병리학회지), Vol.22(2) : 95-100, 2002-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers

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