Cited 0 times in
주의력결핍 과잉행동장애 아동에서 I-123 IPT SPECT로 측정한 기저 신경절 도파민 운반체 밀도
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김찬형 | - |
dc.contributor.author | 남궁기 | - |
dc.contributor.author | 천근아 | - |
dc.contributor.author | 유영훈 | - |
dc.contributor.author | 김영기 | - |
dc.date.accessioned | 2016-05-16T11:03:41Z | - |
dc.date.available | 2016-05-16T11:03:41Z | - |
dc.date.issued | 2002 | - |
dc.identifier.issn | 1017-5717 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/143699 | - |
dc.description.abstract | Objective: ADHD has been known as a psychiatric disorder in childhood associated with dopamine dysregulation. In the present study, we investigated dopamine transporter (DAT) density using I -123N-(3~iodopropen-2yI)-2β-carbomethoxy-3beta- (4-chlorophenyI) tropane (I -123-IPT)-SPECT in children with ADHD on the hypothesis that alterations of DAT density in the basal ganglia were suggestive of dopaminergic dysfunction in children with ADHD. Methods: Nine drug-naive children with ADHD and six normal children were included in the study. We performed brain SPECT two hours after the intravenous administration of 1-123-IPT and made both quantitative and qualitative analyses using the obtained SPECT data. which were reconstructed for the assessment of specific/nonspecific DAT binding ratios in the basal ganglia. We then investigated the correlation between ADHD Rating Scale (ARS) scores of children with ADHD and specific/nonspecific DAT binding ratios in the basal ganglia. Results: Children with ADHD had significantly greater specific/nonspecific DAT binding ratio of the basal ganglia comparing to normal children. However, no significant correlation were found between ARS scores of children with ADHD and specific/nonspecific DAT binding ratio of basal ganglia in children with ADHD. Conclusion: These finding, support the complex dysregulation of the dopaminergic neurotransmitter system in children with ADHD. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | Korean Journal of Psychopharmacology (대한정신약물학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 주의력결핍 과잉행동장애 아동에서 I-123 IPT SPECT로 측정한 기저 신경절 도파민 운반체 밀도 | - |
dc.title.alternative | Dopamine Transporter Density of the Basal Ganglia in Children with Attention Deficit Hyperactivity Disorder Assessed with I-123 IPT SPECT | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Psychiatry (정신과학) | - |
dc.contributor.googleauthor | 천근아 | - |
dc.contributor.googleauthor | 유영훈 | - |
dc.contributor.googleauthor | 김영기 | - |
dc.contributor.googleauthor | 남궁기 | - |
dc.contributor.googleauthor | 김찬형 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01036 | - |
dc.contributor.localId | A01240 | - |
dc.relation.journalcode | J02107 | - |
dc.contributor.alternativeName | Kim, Chan Hyung | - |
dc.contributor.alternativeName | Namkoong, Kee | - |
dc.contributor.affiliatedAuthor | Kim, Chan Hyung | - |
dc.contributor.affiliatedAuthor | Namkoong, Kee | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 13 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 95 | - |
dc.citation.endPage | 103 | - |
dc.identifier.bibliographicCitation | Korean Journal of Psychopharmacology (대한정신약물학회지), Vol.13(2) : 95-103, 2002 | - |
dc.identifier.rimsid | 38607 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.