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성선 자극 호르몬에 의해 유도된 인간 난소내 세포사멸된 난자에서의 StAR 단백질의 발현
DC Field | Value | Language |
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dc.contributor.author | 김세광 | - |
dc.contributor.author | 배상욱 | - |
dc.date.accessioned | 2016-05-16T11:00:06Z | - |
dc.date.available | 2016-05-16T11:00:06Z | - |
dc.date.issued | 2002 | - |
dc.identifier.issn | 0494-4755 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/143570 | - |
dc.description.abstract | Objective: To determine the distribution and expression of steroid acute regulatory (StAR) protein in human oocyte and embryo in relation to apoptosis. Methods: Immuno-labelling and confocal microscopy were applied to examine the localization of StAR protein in human oocytes and embryos. Western blot analysis was also used for qualitative and quantitative assessment of StAR protein expression. Results: There were lipid droplet accumulation in fragmented human oocytes and embryos. StAR protein (30 kDa) expression was detected in human oocytes and embryos. The level of StAR protein expression was lower in the fragmented group than the normal group. Conclusion: The present study provides evidence for involvement of StAR protein in the apoptosis of fragmented oocytes and embryos during in vitro fertilization (IVF) program as well as in the normal development of human oocytes and embryos. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 2140~2145 | - |
dc.relation.isPartOf | Korean Journal of Obstetrics and Gynecology (대한산부인과학회잡지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 성선 자극 호르몬에 의해 유도된 인간 난소내 세포사멸된 난자에서의 StAR 단백질의 발현 | - |
dc.title.alternative | Expression of Steroidogenic Acute regulatory (StAR) Protein during Oocyte Apoptosis in the Gonadotropin-Stimulated Human Ovary | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Obstetrics & Gynecology (산부인과학) | - |
dc.contributor.googleauthor | 김세광 | - |
dc.contributor.googleauthor | 박철홍 | - |
dc.contributor.googleauthor | 양현원 | - |
dc.contributor.googleauthor | 김명신 | - |
dc.contributor.googleauthor | 정경아 | - |
dc.contributor.googleauthor | 배상욱 | - |
dc.contributor.googleauthor | 박기현 | - |
dc.contributor.googleauthor | 조동제 | - |
dc.contributor.googleauthor | 윤용달 | - |
dc.contributor.googleauthor | 송찬호 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00601 | - |
dc.contributor.localId | A01793 | - |
dc.relation.journalcode | J02075 | - |
dc.subject.keyword | StAR protein | - |
dc.subject.keyword | Apoptosis | - |
dc.subject.keyword | Human oocyte | - |
dc.subject.keyword | Embryo | - |
dc.contributor.alternativeName | Kim, Sei Kwang | - |
dc.contributor.alternativeName | Bai, Sang Wook | - |
dc.contributor.affiliatedAuthor | Kim, Sei Kwang | - |
dc.contributor.affiliatedAuthor | Bai, Sang Wook | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 45 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 2140 | - |
dc.citation.endPage | 2145 | - |
dc.identifier.bibliographicCitation | Korean Journal of Obstetrics and Gynecology (대한산부인과학회잡지), Vol.45(12) : 2140-2145, 2002 | - |
dc.identifier.rimsid | 38268 | - |
dc.type.rims | ART | - |
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