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Primary Lymphoma of Bone: Survival and Prognosis

Authors
 Jun Yong Choi  ;  Jee Sook Hahn  ;  Chang Ok Suh  ;  Woo Ick Yang 
Citation
 KOREAN JOURNAL OF INTERNAL MEDICINE, Vol.17(3) : 191-197, 2002 
Journal Title
KOREAN JOURNAL OF INTERNAL MEDICINE
ISSN
 1226-3303 
Issue Date
2002
MeSH
Adolescent ; Adult ; Aged ; BoneNeoplasms/mortality* ; BoneNeoplasms/pathology ; BoneNeoplasms/therapy ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Korea/epidemiology ; Lymphoma/mortality* ; Lymphoma/pathology ; Lymphoma/therapy ; Male ; Middle Aged ; Neoplasm Staging ; Prognosis ; Retrospective Studies ; SurvivalRate
Keywords
Bone and Bones ; Lumphoma ; Survival ; Prognosis
Abstract
Background: Primary lymphoma of bone is a rare disease. There is yet no systematical evaluation of primary lymphoma of bone in Korea. Here we report our experience of sixteen cases with primary lymphoma of bone focusing on the survival. Methods: Sixteen cases, collected for 13 years, were evaluated on the clinical presentation, histologic subtype, stage and treatment outcomes of the primary bone lymphoma. Results: The most common presenting complaint was bone pain. Malignant lymphoma of bone involved a wide variety of sites, the most prevalent site of which in this study was the spine. Most of the cases were in the diffuse large B-cell category. The clinical stage of lymphoma was IEA in two cases, IIEA in three cases, IVEA in five cases and IVEB in three cases. All treated cases received systemic chemotherapy and ten cases among them were treated with combined modality therapy. Median overall survival was not reached after median follow-up period of 28 months and five-year overall survival rate was 54%. Conclusion: More promising therapeutic strategies are needed for survival improvement on more accumulated cases.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
Yonsei Authors
Suh, Chang Ok(서창옥)
Yang, Woo Ick(양우익) ORCID logo https://orcid.org/0000-0002-6084-5019
Choi, Jun Yong(최준용) ORCID logo https://orcid.org/0000-0002-2775-3315
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/143370
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