황화수소에 대한 후각감지역치 및 구취, 흡연, 성 그리고 월경주기에 의한 영향

Abstract

Hydrogen sulfide is the major component of oral bad breath. This study was performed to determine the olfactory detection threshold for hydrogen sulfide in Korean subjects and to evaluate the effect of bad breath, smoking, gender and menstrual cycle on the olfactory detection threshold for hydrogen sulfide. Twenty male smokers, twenty male non-smokers, and ten female non-smokers were included for the study. A 15-step dilution series of hydrogen sulfide gases were prepared by half-1og step from -4 log concentration ppb to 3 log concentration ppb, The olfactory detection threshold for hydrogen sulfide was measured by two-alternative forced-choice single-staircase detection threshold procedure in a double-blinded condition, The geometric mean of the last four staircase reversal points of a total seven reversals was used as the threshold. The threshold values produced by this method were compared by bad breath, smoking, gender and menstrual cycle. The results were as follows; 1. The olfactory detection threshold for hydrogen sulfide in Korean was in the range from 35.5 ppb to 49.0 ppb, 2. There was no significant difference in the olfactory detection threshold for hydrogen sulfide according to the level of oral volatile sulfur compound at the concentration range of no clinical bad breath. 3. There was no significant difference in the olfactory detection threshold for hydrogen sulfide between male smokers and male non-smokers. 4. There was no significant difference in the olfactory detection threshold for hydrogen sulfide between male non-smokers and female non-smokers. 5 Although statistically not significant the olfactory detection threshold for hydrogen sulfide tended to be lowest in the follicular phase of menstrual cycle.