저온 처리한 자가골과 관절 치환술용 인공관절을 이용한 사지구제술

Abstract

Limb salvage using a low heat treated autobone and conventional joint prosthesis was done in 12 patients with nine osteosarcomas, one chondrosarcoma, and two malignant spindle cell sarcomas, composed of six proximal femurs and six proximal humeri. The overall union rate of the low heat treated autobone with normal host bone was 91.7%, and the mean union time was 4.6 months (range, 3-7 months) after surgery. The functional result of the proximal femur and proximal humerus were 76.7% and 56.8%, respectively. Complications were included hip dislocation (8.3%), fracture of the low heat treated bone (16.7%), and absorption of the low heat treated autobone in four of six patients of the humerus (66.7%). The five years survival rate of the low heat treated autobone was 83.3% using Kaplan Meier survival analysis. Based on the results of this study, limb salvage with the low heat treated autobone appears to be effective in treating primary bone sarcoma with proven high survival and low complication rate, circumventing complications of allograft bone.