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Newer neuroleptic treatment for behavioural and psychological symptoms (BPSD) of dementia

DC FieldValueLanguage
dc.contributor.author오병훈-
dc.date.accessioned2016-02-19T11:10:53Z-
dc.date.available2016-02-19T11:10:53Z-
dc.date.issued2001-
dc.identifier.issn1496-3892-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/142578-
dc.description.abstractBACKGROUND: Dementia is a neuropsychiatric disorder characterized by cognitive impairments and behavioural and psychiatric symptoms. Various behavioural and psy- chological symptoms of dementia (BPSD) especially increase the burden to family and society. We studied the treatment efficacy and safety of risperidone and olanzapine on elderly dementia patients. METHODS: The study population consisted of 42 elderly patients who had BPSD with dementia, treated with risperi- done or olanzapine. Clinical safety and efficacy was evalu- ated by Clinical Global Impression (CGI) and side-effects checklist. Mean age was 68.2 ± 5.9 with 16 (38.1%) male and 26 (61.9%) female subjects. The types of dementia among the 42 demented patients were as follows: Alzheimer's dis- ease 25 (59.5%), vascular dementia 10 (23.8%), and other dementia 7 (16.7%). RESULTS: Mean Geriatric Dementia Scale scores was 5.5 ± 1.0. The efficacy of risperidone vs olanzapine was "markedly improved" 12.9% vs 34.0%, "moderately improved" 45.2% vs 29.9%, and "mildly improved" 32.2% vs 36.1% on CGI.The incidence of adverse reactions was 25.8% vs 36.4% respectively. CONCLUSIONS: Risperidone and olanzapine were found to be highly useful and well-tolerated antipsychotic drugs for behavioural and psychological symptoms of dementia between 1-2 mg vs 5-7.5 mg daily dosage respectively. However, proper evaluation of behave-ADAS (Alzheimer's Disease Assessment Scale), IADL (Instrumental Activity of Daily Living) and a larger number of elderly patients must be analyzed.-
dc.description.statementOfResponsibilityopen-
dc.format.extent24~27-
dc.relation.isPartOfGeriatrics Today: Journal of the Canadian Geriatrics Society-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleNewer neuroleptic treatment for behavioural and psychological symptoms (BPSD) of dementia-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Psychiatry (정신과학)-
dc.contributor.googleauthorByoung Hoon Oh-
dc.contributor.googleauthorJUNG HYUN LEE-
dc.contributor.googleauthorJIN SOOK CHEON-
dc.contributor.googleauthorKAE JOON YOO-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02368-
dc.relation.journalcodeJ00944-
dc.contributor.alternativeNameOh, Byong Hoon-
dc.contributor.affiliatedAuthorOh, Byong Hoon-
dc.rights.accessRightsnot available-
dc.citation.volume4-
dc.citation.number1-
dc.citation.startPage24-
dc.citation.endPage27-
dc.identifier.bibliographicCitationGeriatrics Today: Journal of the Canadian Geriatrics Society, Vol.4(1) : 24-27, 2001-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers

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