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이소플라본 섭취수준이 폐경기 여성의 갱년기 증상 및 혈청내 호르몬 변화에 미치는 영향

DC FieldValueLanguage
dc.contributor.author이병석-
dc.date.accessioned2016-02-19T11:10:13Z-
dc.date.available2016-02-19T11:10:13Z-
dc.date.issued2001-
dc.identifier.issn1226-8704-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/142554-
dc.description.abstractObjective: We investigated the effect of isoflavone on postmenopausal symptoms, urinary isoflavone excretion and hormonal changes to know the effect on isoflavone in postmenopausal women. Design and method: 30 postmenopausal women took part in this study. They are divided into 3 subgroups according to the dose of isoflavone supplementation of 100 ㎎/day, 150 ㎎/day, and 200 ㎎/day. Isoflavone were consumed for 6 months. To study the bioavailability of isoflavone, 24-hr urine was collected before and 7 day after each isoflavone supplementation. Initially LH, FSH, Prolactin, E1, E2, testosterone, DHEA-S were measured and 6 months after supplementation of isoflavone. Results: The urinary isoflavone excretion was does dependent in postmenopausal women and average 24-hr urinary recoveries of daidzein and genistein were approximately 15% and 7% respectively. Isoflavone supplementations were effective in reducing the postmenopausal symptoms especially in hot flush(84.6%) and general weakness(69.2%). Serum LH, FSH, E1, E2, prolactin, DHEA-S level were not changed significantly but the level of testosterone increased significantly from 0.20±0 ng/㎖ to 0.51±0.21 ng/㎖ and from 0.26±0.1 ng/㎖ to 0.49±0.3 ng/㎖ in 100㎎ and 150㎎ isoflavone supplementation respectively. but not in 200㎎ isoflavone supplementation. Conclusions: Isoflavone may improve the postmenopausal symptoms by increasing serum testosterone level in postmenopausal women.-
dc.description.statementOfResponsibilityopen-
dc.format.extent54~63-
dc.relation.isPartOfJournal of Korean Society of Menopause (대한폐경학회지)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.title이소플라본 섭취수준이 폐경기 여성의 갱년기 증상 및 혈청내 호르몬 변화에 미치는 영향-
dc.title.alternativeThe Effect Of Isoflavone on Postmenopausal Symptoms and Hormonal Changes in Postmenopausal Women-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Obstetrics & Gynecology (산부인과학)-
dc.contributor.googleauthor원형재-
dc.contributor.googleauthor이병석-
dc.contributor.googleauthor이수경-
dc.contributor.googleauthor최윤-
dc.contributor.googleauthor윤선-
dc.contributor.googleauthor박기현-
dc.contributor.googleauthor조동제-
dc.contributor.googleauthor송찬호-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02795-
dc.relation.journalcodeJ01546-
dc.subject.keywordisoflavone-
dc.subject.keywordpostmenopausal symptom-
dc.subject.keywordgenistein-
dc.subject.keyworddiadzein-
dc.contributor.alternativeNameLee, Byung Seok-
dc.contributor.affiliatedAuthorLee, Byung Seok-
dc.rights.accessRightsfree-
dc.citation.volume7-
dc.citation.number1-
dc.citation.startPage54-
dc.citation.endPage63-
dc.identifier.bibliographicCitationJournal of Korean Society of Menopause (대한폐경학회지), Vol.7(1) : 54-63, 2001-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers

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