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재태 연령에 따른 태아 중뇌 동맥 도플러 지수의 기준치

Other Titles
 Reference Ranges of Doppler Indices in the Fetal Middle Cerebral Artery according to Gestational Age 
 박용원  ;  조재성  ;  권혜경  ;  김영한  ;  이창희 
 Korean Journal of Obstetrics and Gynecology (대한산부인과학회잡지), Vol.44(4) : 734-739, 2001 
Journal Title
Korean Journal of Obstetrics and Gynecology(대한산부인과학회잡지)
Issue Date
Fetal MCA ; Doppler flow resistance index ; fetal hypoxia
Materials and Methods : The subjects were selected from pregnant women receiving antenatal care at Severance Hospital between March 1996 and December 1999. Fetal MCA reference resistance index range according to gestational age were obtained through routine Doppler velocimetry for 4621 normal pregnant women between 24-42 gestational weeks. Those manifesting multiple pregnancy, Diabetes Mellitus, drug abuse, chronic hypertension, fetal congenital anomaly, fetal growth restriction(FGR) with discrepencies of more than 7days and pregnancies complicated by pregnancy induced hypertension (PIH) were excluded. Additionally, the fetal MCA hemodynamic changes were compared for 140 pregnant women with FGR or PIH. The normal ranges for fetal MCA Doppler resistance indices were expressed as mean±SD, and a comparative analysis between the PIH or FGR group and the normal control group was performed. Statistical analysis was done using the SPSS 8.0 program, t-test and the Pearson correlation. Result : The fetal MCA doppler flow resistance indices for normal pregnancies were 0.77±0.006 at 24 weeks and 0.79±0.006 at 28 weeks, demonstrating a statistically significant increase(p<0.05). At 40 weeks the index was 0.71±0.009 showing a significant decrease after 28weeks(p<0.05). There was a tendency for the resistance index to be lower in the PIH/FGR group compared to the normal controls. Conclusion : Constructing a normal reference resistance index range for fetal MCA flow is of high clinical value with regards to predicting fetal well being and understanding the hemodynamics of fetal cerebral perfusion.
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1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Park, Yong Won(박용원)
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