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세포생물학과 Proteomics 응용

Other Titles
 Proteomic application in cell biology (review). 
Authors
 김동욱 
Citation
 Korean Journal of Microbiology (미생물학회지), Vol.37(2) : 109-113, 2001 
Journal Title
 Korean Journal of Microbiology  (미생물학회지) 
ISSN
 0440-2413 
Issue Date
2001
Abstract
As the complete genomic sequences accumulate, the use of global techniques became possible. DNA microarray is a powerful technology for measuring global mRNA levels. This method, however, does not provide information on post-translational modifications of proteins. In addition, mRNA levels do not strictly correlate with protein concentrations, especially for lower-abundance proteins. Therefore, studies at the level of transcription are not sufficient to understand cellular activity. Proteomic techniques to analyze protein expression and function at the large-scale have been developed and used. This review introduces a simple explanation for proteomic analysis and examples of how proteomics is applied in cell biology.
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/142027
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Physiology (생리학교실)
Yonsei Authors
김동욱(Kim, Dong Wook)
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