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분류 불능형 면역결핍증에서 발생한 Lymphoid Interstitial Pneumonia의 Clonality
DC Field | Value | Language |
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dc.contributor.author | 이경아 | - |
dc.date.accessioned | 2016-02-19T10:54:56Z | - |
dc.date.available | 2016-02-19T10:54:56Z | - |
dc.date.issued | 2001 | - |
dc.identifier.issn | 1225-6978 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/141982 | - |
dc.description.abstract | Common variable immunodeficiency (CVID) is a heterogenous syndrome characterized by hypogammaglobulinemia, various immunologic abnormalities and recurrent bacterial infections. Associated immunologic abnormalities consists of various kinds of autoimmune diseases and lymphoproliferative disorders. The lymphoproliferative disorder take several forms, such as malignant lymphoma, atypical lymphoid hyperplasia, and beniegn lymphoid hyperplasia. Lymphocytic interstitial pneumonia (LIP), which is a kind of atypical lymphoid hyperplasia, develop in young age groups and has controversy on its clonality. We experienced a 14-year-old female patient with LIP and CVID. We analysed the third complementarity-determining region (CDR3) of the immunoglobulin heavy chain gene for clonality analysis. Clonality analysis of lung biopsy specimen revealed that 6 of 13 colony and 4 of 13 colony have identical sequences respectively. We speculate that one of these 2 lymphoid cell clone may develop into malignant lymphoma in the future. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 355~360 | - |
dc.relation.isPartOf | Korean Journal of Pediatric Hematology-Oncology (대한소아혈액종양학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 분류 불능형 면역결핍증에서 발생한 Lymphoid Interstitial Pneumonia의 Clonality | - |
dc.title.alternative | Clonality of Lymphocytic Interstitial Pneumonia in Common Variable Immunodeficiency | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학) | - |
dc.contributor.googleauthor | 강계월 | - |
dc.contributor.googleauthor | 이영섭 | - |
dc.contributor.googleauthor | 김황민 | - |
dc.contributor.googleauthor | 예병일 | - |
dc.contributor.googleauthor | 김태현 | - |
dc.contributor.googleauthor | 정순희 | - |
dc.contributor.googleauthor | 김동진 | - |
dc.contributor.googleauthor | 이경아 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02647 | - |
dc.relation.journalcode | J02096 | - |
dc.subject.keyword | common variable immunodeficiency | - |
dc.subject.keyword | lymphocytic interstitial pneumonia | - |
dc.subject.keyword | CDR3 | - |
dc.subject.keyword | Malignant lymphoma | - |
dc.contributor.alternativeName | Lee, Kyung A | - |
dc.contributor.affiliatedAuthor | Lee, Kyung A | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 8 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 355 | - |
dc.citation.endPage | 360 | - |
dc.identifier.bibliographicCitation | Korean Journal of Pediatric Hematology-Oncology (대한소아혈액종양학회지), Vol.8(2) : 355-360, 2001 | - |
dc.identifier.rimsid | 35901 | - |
dc.type.rims | ART | - |
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