점막연관 림프조직형 위 림프종과 병발한 조기 위암 1예

Abstract

Multiple primary gastric malignant tumors are reported to constitute 1.25% of all gastric carcinomas. The simultaneous coexistence of adenocarcinoma and mucosa-associated lymphoid tissue (MALT) lymphoma of the stomach is very rare. Moreover, both gastric carcinoma and primary gastric MALT lymphoma are considered to be related with Helicobacter pylori (H. pylori) infection. However, the precise role of H. pylori in gastric carcinogenesis and lymphomatogenesis still remains as a challenging part of gastroenterology. We present here a rare case of simultaneous gastric MALT lymphoma and adenocarcinoma of the stomach in a patient with evidence of H. pylori infection. The MALT lymphoma was successfully treated after the eradication of H. pylori. However, the gastroscopic biopsy of the other lesion of the stomach for 3-month follow-up demonstrated signet-ring cell carcinoma. We report the case of this synchronous neoplasm of the stomach related to H. pylori infection with a review of literature.