Cited 3 times in
Prediction of survival by applying current prognostic models in diffuse large B-cell lymphoma treated with R-CHOP followed by autologous transplantation
DC Field | Value | Language |
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dc.contributor.author | 정준원 | - |
dc.date.accessioned | 2016-02-04T12:01:19Z | - |
dc.date.available | 2016-02-04T12:01:19Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 2287-979X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/141717 | - |
dc.description.abstract | BACKGROUND: Among the currently available prognostic models for diffuse large B-cell lymphoma (DLBCL), we investigated to determine which is most adoptable for DLBCL patients treated with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) followed by upfront autologous stem cell transplantation (auto-SCT). METHODS: We retrospectively evaluated survival differences among risk groups based on the International Prognostic Index (IPI), the age-adjusted IPI (aaIPI), the revised IPI (R-IPI), and the National Comprehensive Cancer Network IPI (NCCN-IPI) at diagnosis in 63 CD20-positive DLBCL patients treated with R-CHOP followed by upfront auto-SCT. RESULTS: At the time of auto-SCT, 74.6% and 25.4% of patients had achieved complete remission and partial remission after R-CHOP, respectively. As a whole, the 5-year overall (OS) and progression-free survival (PFS) rates were 78.8% and 74.2%, respectively. The 5-year OS and PFS rates according to the IPI, aaIPI, R-IPI, and NCCN-IPI did not significantly differ among the risk groups for each prognostic model (P-values for OS: 0.255, 0.337, 0.881, and 0.803, respectively; P-values for PFS: 0.177, 0.904, 0.295, and 0.609, respectively). CONCLUSION: There was no ideal prognostic model among those currently available for CD20-positive DLBCL patients treated with R-CHOP followed by upfront auto-SCT. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 160~166 | - |
dc.relation.isPartOf | BLOOD RESEARCH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Prediction of survival by applying current prognostic models in diffuse large B-cell lymphoma treated with R-CHOP followed by autologous transplantation | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Hong Ghi Lee | - |
dc.contributor.googleauthor | Sung-Yong Kim | - |
dc.contributor.googleauthor | Inho Kim | - |
dc.contributor.googleauthor | Yeo-Kyeoung Kim | - |
dc.contributor.googleauthor | Jeong-A Kim | - |
dc.contributor.googleauthor | Yang Soo Kim | - |
dc.contributor.googleauthor | Ho Sup Lee | - |
dc.contributor.googleauthor | Jinny Park | - |
dc.contributor.googleauthor | Seok Jin Kim | - |
dc.contributor.googleauthor | Hyeok Shim | - |
dc.contributor.googleauthor | Hyeon Seok Eom | - |
dc.contributor.googleauthor | Byeong-Bae Park | - |
dc.contributor.googleauthor | Junglim Lee | - |
dc.contributor.googleauthor | Sung Kyu Park | - |
dc.contributor.googleauthor | June-Won Cheong | - |
dc.contributor.googleauthor | Keon Woo Park | - |
dc.identifier.doi | 10.5045/br.2015.50.3.160 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03729 | - |
dc.relation.journalcode | J00346 | - |
dc.identifier.eissn | 2288-0011 | - |
dc.identifier.pmid | 26457283 | - |
dc.subject.keyword | Autologous transplantation | - |
dc.subject.keyword | Diffuse large B-cell lymphoma | - |
dc.subject.keyword | Hematopoietic stem cell transplantation | - |
dc.subject.keyword | Prognostic groups | - |
dc.subject.keyword | Rituximab | - |
dc.contributor.alternativeName | Cheong, June Won | - |
dc.contributor.affiliatedAuthor | Cheong, June-Won | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 50 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 160 | - |
dc.citation.endPage | 166 | - |
dc.identifier.bibliographicCitation | BLOOD RESEARCH, Vol.50(3) : 160-166, 2015 | - |
dc.identifier.rimsid | 30841 | - |
dc.type.rims | ART | - |
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