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Predictive Factors for Endoscopic Visibility and Strategies for Pre-endoscopic Prokinetics Use in Patients with Upper Gastrointestinal Bleeding
DC Field | Value | Language |
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dc.contributor.author | 박재준 | - |
dc.contributor.author | 윤영훈 | - |
dc.date.accessioned | 2016-02-04T12:01:01Z | - |
dc.date.available | 2016-02-04T12:01:01Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 0163-2116 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/141705 | - |
dc.description.abstract | BACKGROUND: Although current guideline recommends selective use of pre-endoscopic prokinetics to increase diagnostic yield in upper gastrointestinal bleeding (UGIB) patients, no data to guide the use of these drugs are available. AIMS: We aimed to investigate predictive factors for endoscopic visibility and develop simple and useful strategies for pre-endoscopic prokinetics use in UGIB patients. METHODS: A total of 220 consecutive patients who underwent upper endoscopy for suspicious UGIB were enrolled. Patients were randomly allocated to either a training or a validation set at a 2:1 ratio. Significant parameters on univariate analysis were subsequently tested by a classification and regression tree (CART) analysis. RESULTS: Time to endoscopy and nasogastric aspirate findings were independently related to endoscopic visibility. The CART analysis generated algorithms proposed sequential use of time to endoscopy (≤5.2 vs. >5.2 h) and nasogastric aspirate findings (red blood or coffee rounds vs. clear aspirate) for predicting endoscopic visibility. Prediction of unacceptable visibility in the validation set produced sensitivity, specificity, positive predictive value, and negative predictive value of 75.8, 67.5, 65.8, and 77.1 %, respectively. Accurate prediction for visibility was identified in 52 of 73 patients (71.2 %). CONCLUSIONS: Time to endoscopy and nasogastric aspirate findings were independently related to endoscopic visibility in patients with UGIB. A decision-tree model incorporating these two variables may be useful for selecting UGIB patients who benefit from pre-endoscopic prokinetics use. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 957~965 | - |
dc.relation.isPartOf | DIGESTIVE DISEASES AND SCIENCES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Decision Trees* | - |
dc.subject.MESH | Endoscopy, Gastrointestinal* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Gastrointestinal Agents/administration & dosage* | - |
dc.subject.MESH | Gastrointestinal Hemorrhage/diagnosis* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Preoperative Period | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Upper Gastrointestinal Tract/drug effects* | - |
dc.title | Predictive Factors for Endoscopic Visibility and Strategies for Pre-endoscopic Prokinetics Use in Patients with Upper Gastrointestinal Bleeding | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Jun Uk Lim | - |
dc.contributor.googleauthor | Jae Jun Park | - |
dc.contributor.googleauthor | Young Hoon Youn | - |
dc.contributor.googleauthor | Sunyong Kim | - |
dc.contributor.googleauthor | Jung Won Jeon | - |
dc.contributor.googleauthor | Sung Won Jung | - |
dc.contributor.googleauthor | Hyun Phil Shin | - |
dc.contributor.googleauthor | Jae Myung Cha | - |
dc.contributor.googleauthor | Kwang Ro Joo | - |
dc.contributor.googleauthor | Joung Il Lee | - |
dc.identifier.doi | 10.1007/s10620-014-3393-y | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01636 | - |
dc.contributor.localId | A02583 | - |
dc.relation.journalcode | J00737 | - |
dc.identifier.eissn | 1573-2568 | - |
dc.identifier.pmid | 25326116 | - |
dc.identifier.url | http://link.springer.com/article/10.1007%2Fs10620-014-3393-y | - |
dc.subject.keyword | Upper gastrointestinal bleeding | - |
dc.subject.keyword | Prokinetics | - |
dc.subject.keyword | Endoscopic visibility | - |
dc.subject.keyword | Decision tree | - |
dc.contributor.alternativeName | Park, Jae Jun | - |
dc.contributor.alternativeName | Youn, Young Hoon | - |
dc.contributor.affiliatedAuthor | Park, Jae Jun | - |
dc.contributor.affiliatedAuthor | Youn, Young Hoon | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 60 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 957 | - |
dc.citation.endPage | 965 | - |
dc.identifier.bibliographicCitation | DIGESTIVE DISEASES AND SCIENCES, Vol.60(4) : 957-965, 2015 | - |
dc.identifier.rimsid | 30829 | - |
dc.type.rims | ART | - |
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