Cited 17 times in
Associations between serum 25-hydroxyvitamin D and bone mineral density and proximal femur geometry in Koreans: the Korean National Health and Nutrition Examination Survey (KNHANES) 2008-2009
DC Field | Value | Language |
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dc.contributor.author | 이유미 | - |
dc.contributor.author | 임승길 | - |
dc.contributor.author | 황세나 | - |
dc.date.accessioned | 2016-02-04T12:00:47Z | - |
dc.date.available | 2016-02-04T12:00:47Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 0937-941X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/141697 | - |
dc.description.abstract | The association between 25-hydroxyvitamin D (25(OH)D) levels and bone mineral density (BMD) and proximal femur bone geometry was examined in the Korean population. A positive relationship between skeletal health and 25(OH)D levels was observed. However, there were no significant differences in skeletal health between the groups with 25(OH)D level of 50-75 nmol/L and greater than 75 nmol/L. INTRODUCTION: Vitamin D plays an important role in calcium and phosphate homeostasis and normal mineralization of bone. However, the optimal level of vitamin D for skeletal health has not been clearly established. We analyzed the associations between serum 25(OH)D and BMD and proximal femur bone geometry and determined the optimal 25(OH)D level. METHODS: This was a cross-sectional study of 10,062 participants (20-95 years, 4,455 men, 5,607 women) in the Fourth Korea National Health and Nutrition Examination Surveys (KNHANES IV) conducted from 2008 to 2009. Participants were divided into groups according to 25(OH)D level (<25, 25-50, 50-75, and ≥75 nmol/L). BMD and proximal femur geometric indices were measured. RESULTS: The group with 25(OH)D levels of 50-75 nmol/L had greater bone density values, with the exception of the lumbar spine, and also had greater femur neck cortical thickness, cross-sectional area, and cross-sectional moment of inertia, as well as a lesser buckling ratio than the groups with 25(OH)D level of 25-50 nmol/L and less than 25 nmol/L. However, there were no significant differences in BMD and proximal femur geometry properties between the groups with 50-75 nmol/L and greater than 75 nmol/L of 25(OH)D. CONCLUSION: The skeletal outcomes, including BMD and proximal femur geometric indices observed in this study, suggest that serum 25(OH)D levels of 50 to <75 nmol/L are optimal for skeletal health. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 163~171 | - |
dc.relation.isPartOf | OSTEOPOROSIS INTERNATIONAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Absorptiometry, Photon/methods | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Anthropometry/methods | - |
dc.subject.MESH | Bone Density/physiology* | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Femur/anatomy & histology* | - |
dc.subject.MESH | Femur/physiology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Nutrition Surveys | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Vitamin D/analogs & derivatives* | - |
dc.subject.MESH | Vitamin D/blood | - |
dc.subject.MESH | Vitamin D Deficiency/epidemiology | - |
dc.subject.MESH | Vitamin D Deficiency/pathology | - |
dc.subject.MESH | Vitamin D Deficiency/physiopathology | - |
dc.subject.MESH | Young Adult | - |
dc.title | Associations between serum 25-hydroxyvitamin D and bone mineral density and proximal femur geometry in Koreans: the Korean National Health and Nutrition Examination Survey (KNHANES) 2008-2009 | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | S. Hwang | - |
dc.contributor.googleauthor | H. S. Choi | - |
dc.contributor.googleauthor | K. M. Kim | - |
dc.contributor.googleauthor | Y. Rhee | - |
dc.contributor.googleauthor | S. K. Lim | - |
dc.identifier.doi | 10.1007/s00198-014-2877-0 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03012 | - |
dc.contributor.localId | A03375 | - |
dc.contributor.localId | A04468 | - |
dc.relation.journalcode | J02451 | - |
dc.identifier.eissn | 1433-2965 | - |
dc.identifier.pmid | 25262060 | - |
dc.identifier.url | http://link.springer.com/article/10.1007%2Fs00198-014-2877-0 | - |
dc.subject.keyword | Bone geometry | - |
dc.subject.keyword | Bone mineral density | - |
dc.subject.keyword | Population study | - |
dc.subject.keyword | Vitamin D | - |
dc.contributor.alternativeName | Rhee, Yumie | - |
dc.contributor.alternativeName | Lim, Sung Kil | - |
dc.contributor.alternativeName | Hwang, Se Na | - |
dc.contributor.affiliatedAuthor | Rhee, Yumie | - |
dc.contributor.affiliatedAuthor | Lim, Sung Kil | - |
dc.contributor.affiliatedAuthor | Hwang, Se Na | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 26 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 163 | - |
dc.citation.endPage | 171 | - |
dc.identifier.bibliographicCitation | OSTEOPOROSIS INTERNATIONAL, Vol.26(1) : 163-171, 2015 | - |
dc.identifier.rimsid | 30824 | - |
dc.type.rims | ART | - |
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