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Generation of Demyelination through Use of M. leprae-specific phenolic glycolipid-1 (PGL-1)

Authors
 Kim, Ji-Young  ;  Choi, Chang-Shik  ;  Hong, Seong-Karp 
Citation
 Rapid Communication in Photoscience, Vol.4(2) : 48-49, 2015 
Journal Title
 Rapid Communication in Photoscience 
ISSN
 2288-4564 
Issue Date
2015
Abstract
For myelination, Schwann cells and neuron cells from dorsal root ganglion (DRG) of rat embryos (E16) were cultured in vitro system. The purified DRG cells with anti-mitotic agents and purified Schwann cells were cocultured and then accomplished myelination processing. Treatment of M. leprae-specific phenolic glycolipid-1 (PGL-1) into this coculture system was performed and then accomplished demyelination. Therefore, we identified demyelination processing using antibody of myelin basic protein (MBP).
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DOI
10.5857/RCP.2015.4.2.48
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실)
Yonsei Authors
김지영(Kim, Ji Young) ORCID logo https://orcid.org/0000-0001-5822-0338
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/141672
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