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Generation of Demyelination through Use of M. leprae-specific phenolic glycolipid-1 (PGL-1)

Authors
 Kim, Ji-Young  ;  Choi, Chang-Shik  ;  Hong, Seong-Karp 
Citation
 Rapid Communication in Photoscience, Vol.4(2) : 48-49, 2015 
Journal Title
Rapid Communication in Photoscience
ISSN
 2288-4564 
Issue Date
2015
Keywords
demyelination ; phenolic glycolipid-1 ; M. leprae ; myelin basic protein
Abstract
For myelination, Schwann cells and neuron cells from dorsal root ganglion (DRG) of rat embryos (E16) were cultured in vitro system. The purified DRG cells with anti-mitotic agents and purified Schwann cells were cocultured and then accomplished myelination processing. Treatment of M. leprae-specific phenolic glycolipid-1 (PGL-1) into this coculture system was performed and then accomplished demyelination. Therefore, we identified demyelination processing using antibody of myelin basic protein (MBP).
Files in This Item:
T201504124.pdf Download
DOI
10.5857/RCP.2015.4.2.48
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Ji Young(김지영) ORCID logo https://orcid.org/0000-0001-5822-0338
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/141672
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