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Applying the bacterial meningitis score in children with cerebrospinal fluid pleocytosis: a single center's experience

DC FieldValueLanguage
dc.contributor.author강훈철-
dc.contributor.author권혜은-
dc.contributor.author김흥동-
dc.contributor.author이준수-
dc.date.accessioned2016-02-04T11:56:40Z-
dc.date.available2016-02-04T11:56:40Z-
dc.date.issued2015-
dc.identifier.issn1738-1061-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/141546-
dc.description.abstractPURPOSE: The widespread introduction of bacterial conjugate vaccines has decreased the risk of cerebrospinal fluid (CSF) pleocytosis due to bacterial meningitis (BM) in children. However, most patients with CSF pleocytosis are hospitalized and treated with parenteral antibiotics for several days. The bacterial meningitis score (BMS) is a validated multivariate model derived from a pediatric population in the postconjugate vaccine era and has been evaluated in several studies. In the present study, we examined the usefulness of BMS in South Korean patients. METHODS: This study included 1,063 patients with CSF pleocytosis aged between 2 months and 18 years. The BMS was calculated for all patients, and the sensitivity and negative predictive value (NPV) of the test were evaluated. RESULTS: Of 1,063 patients, 1,059 (99.6%) had aseptic meningitis (AM). Only four patients (0.4%) had BM. The majority of patients (98%) had a BMS of ≤1, indicating a diagnosis of AM. The BMS was 0 in 635 patients (60%) and 1 in 405 patients (38%). All four BM patients had a BMS of ≥4. CONCLUSION: To our knowledge, this is the first study to investigate the diagnostic strength of the BMS in South Korea. In our study, the BMS showed 100% sensitivity and 100% NPV. Therefore, we believe that the BMS is a good clinical prediction rule to identify children with CSF pleocytosis who are at a risk of BM.-
dc.description.statementOfResponsibilityopen-
dc.format.extent251~255-
dc.relation.isPartOfKorean Journal of Pediatrics-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleApplying the bacterial meningitis score in children with cerebrospinal fluid pleocytosis: a single center's experience-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pediatrics (소아과학)-
dc.contributor.googleauthorJungpyo Lee-
dc.contributor.googleauthorHyeeun Kwon-
dc.contributor.googleauthorJoon Soo Lee-
dc.contributor.googleauthorHeung Dong Kim-
dc.contributor.googleauthorHoon Chul Kang-
dc.identifier.doi10.3345/kjp.2015.58.7.251-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00102-
dc.contributor.localIdA00267-
dc.contributor.localIdA01208-
dc.contributor.localIdA03177-
dc.relation.journalcodeJ02100-
dc.identifier.pmid26300939-
dc.subject.keywordAseptic meningitis-
dc.subject.keywordBacterial meningitis-
dc.subject.keywordClinical prediction rule-
dc.contributor.alternativeNameKang, Hoon Chul-
dc.contributor.alternativeNameKwon, Hye Eun-
dc.contributor.alternativeNameKim, Heung Dong-
dc.contributor.alternativeNameLee, Joon Soo-
dc.contributor.affiliatedAuthorKang, Hoon Chul-
dc.contributor.affiliatedAuthorKwon, Hye Eun-
dc.contributor.affiliatedAuthorKim, Heung Dong-
dc.contributor.affiliatedAuthorLee, Joon Soo-
dc.rights.accessRightsfree-
dc.citation.volume58-
dc.citation.number7-
dc.citation.startPage251-
dc.citation.endPage255-
dc.identifier.bibliographicCitationKorean Journal of Pediatrics, Vol.58(7) : 251-255, 2015-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers

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