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Evaluating hypertrophic thyroidectomy scar outcomes after treatment with triamcinolone injections and copper bromide laser therapy

Authors
 Hye Rang On  ;  Sang Hee Lee  ;  Yong Sang Lee  ;  Hang-Seok Chang  ;  CheongSoo Park  ;  Mi Ryung Roh 
Citation
 LASERS IN SURGERY AND MEDICINE, Vol.47(6) : 479-484, 2015 
Journal Title
LASERS IN SURGERY AND MEDICINE
ISSN
 0196-8092 
Issue Date
2015
MeSH
Adult ; Anti-Inflammatory Agents/therapeutic use* ; Cicatrix, Hypertrophic/etiology ; Cicatrix, Hypertrophic/therapy* ; Combined Modality Therapy ; Female ; Humans ; Injections, Intralesional ; Lasers, Gas/therapeutic use* ; Male ; Middle Aged ; Postoperative Complications/therapy* ; Retrospective Studies ; Thyroidectomy* ; Treatment Outcome ; Triamcinolone Acetonide/therapeutic use*
Keywords
copper bromide laser ; hypertrophic scar ; prognostic factor ; treatment outcomes
Abstract
BACKGROUND AND OBJECTIVES: Postoperative hypertrophic scar following thyroidectomy can be a major concern due to its disfiguring appearance. Recently, copper bromide laser (CBL) and intralesional triamcinolone injection (TA ILI) have been used to treat hypertrophic thyroidectomy scars. Data regarding the number of treatment sessions needed to reach a certain endpoint and the prognostic factors that affect treatment duration are unknown. The aim of this study was to evaluate the number of treatment sessions required to reduce VSS score by 50%, which was regarded as the treatment endpoint, and to investigate the factors that influence treatment duration when using CBL and TA ILI.

MATERIALS AND METHODS: A total of 67 patients were enrolled in this study. Baseline characteristics of the patients including age, sex, body mass index (BMI), distance of the scar from the sternal notch, time of development of the hypertrophic scar, sternocleidomastoid (SCM) muscle prominence, and date of operation were collected on the first visit. They were treated with CBL and TA. The concentration of triamcinolone used was 2.5 mg/ml or 5 mg/ml according to the pliability score of each scar.

RESULTS: The mean number of treatment sessions required to achieve the endpoint was 3.85 ± 1.25. Among the variables assessed, location of the scar near the sternal notch (P = 0.020) and patient BMI (P = 0.001) were associated with the increasing number of treatment sessions.

CONCLUSION: In our study cohort, four treatments were required to reduce the VSS of thyroidectomy scars by 50% when using a combination treatment of CBL and low concentration TA ILI. Also, scar location and patient BMI are factors that affect treatment outcome.
Full Text
http://onlinelibrary.wiley.com/doi/10.1002/lsm.22375/abstract
DOI
10.1002/lsm.22375
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Roh, Mi Ryung(노미령) ORCID logo https://orcid.org/0000-0002-6285-2490
Lee, Sang Hee(이상희)
Lee, Yong Sang(이용상) ORCID logo https://orcid.org/0000-0002-8234-8718
Chang, Hang Seok(장항석) ORCID logo https://orcid.org/0000-0002-5162-103X
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/141432
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