0 114

Surgical Treatment and Outcomes in Patients With Intestinal Behçet Disease: Long-term Experience of a Single Large-Volume Center

DC FieldValueLanguage
dc.contributor.author김남규-
dc.contributor.author김창우-
dc.contributor.author민병소-
dc.contributor.author백세진-
dc.contributor.author백승혁-
dc.contributor.author장현아-
dc.contributor.author조민수-
dc.contributor.author허혁-
dc.date.accessioned2016-02-04T11:52:40Z-
dc.date.available2016-02-04T11:52:40Z-
dc.date.issued2015-
dc.identifier.issn0012-3706-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/141400-
dc.description.abstractBACKGROUND: Few studies have examined the surgical treatment of intestinal Behçet disease. Consequently, there is currently no standard surgical treatment for intestinal Behçet disease. Instead, treatment is empirical and symptom based. OBJECTIVE: Our aim was to evaluate the clinical course after surgery and determine the appropriate surgical options for intestinal Behçet disease. DESIGN: Medical charts of patients who underwent surgery for intestinal Behçet were retrospectively reviewed. SETTINGS: The study was conducted at a tertiary referral center. PATIENTS: Ninety-one patients who underwent surgical treatment for intestinal Behçet disease between January 1995 and December 2012 were included in this study. MAIN OUTCOME MEASURES: Primary outcomes measured were patient demographics, clinical characteristics, operative and postoperative outcomes, and long-term follow-up data. RESULTS: Surgical treatment was mainly in response to intractability to medical treatment (56.0%), and 19.8% of patients underwent an emergency operation. Surgery was performed laparoscopically in 33.0% of the patients. Most patients received an ileocecectomy (39.6%) or a right hemicolectomy (34.1%). Twenty-eight patients (30.8%) experienced postoperative morbidities, and 8 patients (8.8%) required reoperations. There were 3 deaths. Reoperation was required for recurrent disease in 32 patients during the long-term follow-up, and the 5-year cumulative reoperation rate was 31.2% (95% CI, 20.4%-42.0%). Among those requiring a second operation, 53.1% were segmental colonic resections that included the previous anastomosis. From multivariable Cox regression analysis, independent predictors of surgical recurrence included postoperative use of steroids (HR = 2.85 (95% CI, 1.21-6.75); p = 0.02), postoperative complications (HR = 2.42 (95% CI, 1.12-5.22); p = 0.03), and BMI (HR per 1-kg/m increase in BMI = 0.90 (95% CI, 0.82-0.99); p = 0.04). LIMITATIONS: This study was designed retrospectively and had a small sample size. CONCLUSIONS: Patients treated surgically for intestinal Behçet disease frequently have postoperative complications and the need for a stoma and have a high risk of recurrence.-
dc.description.statementOfResponsibilityopen-
dc.format.extent575~581-
dc.relation.isPartOfDiseases of the Colon & Rectum-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleSurgical Treatment and Outcomes in Patients With Intestinal Behçet Disease: Long-term Experience of a Single Large-Volume Center-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Surgery (외과학)-
dc.contributor.googleauthorBaek, Se Jin-
dc.contributor.googleauthorKim, Chang Woo-
dc.contributor.googleauthorCho, Min Soo-
dc.contributor.googleauthorJang, Hyun A.-
dc.contributor.googleauthorBaik, Seung Hyuk-
dc.contributor.googleauthorHur, Hyuk-
dc.contributor.googleauthorMin, Byung Soh-
dc.contributor.googleauthorKim, Nam Kyu-
dc.identifier.doi10.1097/DCR.0000000000000373-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01046-
dc.contributor.localIdA00353-
dc.contributor.localIdA01402-
dc.contributor.localIdA01820-
dc.contributor.localIdA01827-
dc.contributor.localIdA03492-
dc.contributor.localIdA03817-
dc.contributor.localIdA04373-
dc.relation.journalcodeJ00744-
dc.identifier.urlhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00003453-201506000-00004&LSLINK=80&D=ovft-
dc.contributor.alternativeNameKim, Nam Kyu-
dc.contributor.alternativeNameKim, Chang Woo-
dc.contributor.alternativeNameMin, Byung Soh-
dc.contributor.alternativeNameBaek, Se Jin-
dc.contributor.alternativeNameBaik, Seung Hyuk-
dc.contributor.alternativeNameJang, Hyun A-
dc.contributor.alternativeNameCho, Min Soo-
dc.contributor.alternativeNameHur, Hyuk-
dc.contributor.affiliatedAuthorKim, Chang Woo-
dc.contributor.affiliatedAuthorKim, Nam Kyu-
dc.contributor.affiliatedAuthorMin, Byung Soh-
dc.contributor.affiliatedAuthorBaek, Se Jin-
dc.contributor.affiliatedAuthorBaik, Seung Hyuk-
dc.contributor.affiliatedAuthorJang, Hyun A-
dc.contributor.affiliatedAuthorCho, Min Soo-
dc.contributor.affiliatedAuthorHur, Hyuk-
dc.rights.accessRightsnot free-
dc.citation.volume58-
dc.citation.number6-
dc.citation.startPage575-
dc.citation.endPage581-
dc.identifier.bibliographicCitationDiseases of the Colon & Rectum, Vol.58(6) : 575-581, 2015-
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실)

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.