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Bone Mineral Density Changes after Orchiectomy using a Scrotal Approach in Rats

DC FieldValueLanguage
dc.contributor.author진동규-
dc.contributor.author구성욱-
dc.contributor.author김경현-
dc.contributor.author김근수-
dc.contributor.author김종열-
dc.contributor.author류달성-
dc.contributor.author박정윤-
dc.contributor.author조용은-
dc.date.accessioned2016-02-04T11:51:21Z-
dc.date.available2016-02-04T11:51:21Z-
dc.date.issued2015-
dc.identifier.issn1738-2262-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/141352-
dc.description.abstractOBJECTIVE: To investigate a suitable animal model for studies of male osteoporosis. Osteoporosis has a particularly high incidence in postmenopausal women, resulting in a substantial amount of research with respect to this disease in women. However, research on osteoporosis in men is still lacking. METHODS: Twenty 10-week-old male Sprague Dawley rats were used in this study, including 4 rats used to establish a baseline bone mineral density (BMD). The other 16 rats were divided into two groups: a sham surgery group (n=8), which underwent a sham operation, and an orchiectomized rat group (OCX) (n=8), which underwent bilateral OCX at 10 weeks of age. Bone mineral density was measured in 4 rats from both the sham surgery group and the OCX group 8 weeks after the surgery, while BMD in the remainder of the rats was measured 10 weeks post-surgery. RESULTS: Femoral BMD at 8 weeks post-surgery was found to be significantly lower in the OCX group compared to the sham group; a finding that was also similar 10 weeks post-surgery. CONCLUSION: 8 weeks after undergoing orchiectomy performed via a scrotal, white rats are a suitable model for studies of male osteoporosis.-
dc.description.statementOfResponsibilityopen-
dc.format.extent55~59-
dc.relation.isPartOfKorean Journal of Spine-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleBone Mineral Density Changes after Orchiectomy using a Scrotal Approach in Rats-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Neurosurgery (신경외과학)-
dc.contributor.googleauthorSeong Jun Ryu-
dc.contributor.googleauthorDal Sung Ryu-
dc.contributor.googleauthorJong Yul Kim-
dc.contributor.googleauthorJeong Yoon Park-
dc.contributor.googleauthorKyung Hyun Kim-
dc.contributor.googleauthorDong Kyu Chin-
dc.contributor.googleauthorKeun Su Kim-
dc.contributor.googleauthorYong Eun Cho-
dc.contributor.googleauthorSung Uk Kuh-
dc.identifier.doi10.14245/kjs.2015.12.2.55-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03979-
dc.contributor.localIdA00196-
dc.contributor.localIdA00308-
dc.contributor.localIdA00330-
dc.contributor.localIdA00924-
dc.contributor.localIdA01322-
dc.contributor.localIdA01650-
dc.contributor.localIdA03865-
dc.relation.journalcodeJ02116-
dc.identifier.pmid26217383-
dc.subject.keywordAnimal model-
dc.subject.keywordBone mineral density-
dc.subject.keywordFemur-
dc.subject.keywordMale-
dc.subject.keywordOrchiectomy-
dc.subject.keywordOsteoporosis-
dc.contributor.alternativeNameChin, Dong Kyu-
dc.contributor.alternativeNameKuh, Sung Uk-
dc.contributor.alternativeNameKim, Kyung Hyun-
dc.contributor.alternativeNameKim, Keun Su-
dc.contributor.alternativeNameKim, Jong Yul-
dc.contributor.alternativeNameRyu, Dal Sung-
dc.contributor.alternativeNamePark, Jeong Yoon-
dc.contributor.alternativeNameCho, Yong Eun-
dc.contributor.affiliatedAuthorChin, Dong Kyu-
dc.contributor.affiliatedAuthorKuh, Sung Uk-
dc.contributor.affiliatedAuthorKim, Kyung Hyun-
dc.contributor.affiliatedAuthorKim, Keun Su-
dc.contributor.affiliatedAuthorKim, Jong Yul-
dc.contributor.affiliatedAuthorRyu, Dal Sung-
dc.contributor.affiliatedAuthorPark, Jeong Yoon-
dc.contributor.affiliatedAuthorCho, Yong Eun-
dc.rights.accessRightsfree-
dc.citation.volume12-
dc.citation.number2-
dc.citation.startPage55-
dc.citation.endPage59-
dc.identifier.bibliographicCitationKorean Journal of Spine, Vol.12(2) : 55-59, 2015-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers

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