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Combined Algorithm Using a Poor Increase in Inferior P-Wave Amplitude During Sympathetic Stimulation and Sinus Node Recovery Time for the Diagnosis of Sick Sinus Syndrome

DC FieldValueLanguage
dc.contributor.author박희남-
dc.contributor.author엄재선-
dc.contributor.author이문형-
dc.contributor.author정보영-
dc.date.accessioned2016-02-04T11:50:17Z-
dc.date.available2016-02-04T11:50:17Z-
dc.date.issued2015-
dc.identifier.issn1346-9843-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/141314-
dc.description.abstractBACKGROUND: This study sought to evaluate whether a poor increase in inferior P-wave amplitude during sympathetic stimulation might be a helpful diagnostic tool for sick sinus syndrome (SSS).Methods and Results:Three-dimensional electroanatomic mapping of the right atrium, inferior P-wave amplitude and conventional corrected sinus node recovery time (CSNRT) were compared in 112 consecutive atrial fibrillation (AF) patients with (n=21) and without SSS (n=91). The significant cranial shift of earliest activation site (EAS) (the distance from the superior vena cava to the EAS: 11.1 vs. 5.9 mm, P<0.001) and the increases of inferior P-wave amplitudes during isoproterenol infusion (all P<0.001) were observed in patients without SSS. However, cranial shift of EAS (16.5 vs. 14.2 mm, P=0.375) and P-wave amplitude increases were not observed in those with SSS. Although CSNRT >550 ms showed a sensitivity of 50% and specificity of 84% for diagnosing SSS, poor increases of P-waves amplitude in lead aVF (<0.1 mV) during isoproterenol infusion showed an improved sensitivity of 71% and specificity of 89%. Finally, the combined algorithm using CSNRT >550 ms and poor increase of P-waves amplitude in lead aVF showed more improved diagnostic accuracy (sensitivity 89%, specificity 75%). CONCLUSIONS: A combined algorithm using inferior P-wave amplitude showed improved performance for the diagnosis of SSS compared with CSNRT >550 ms alone.-
dc.description.statementOfResponsibilityopen-
dc.format.extent2148~2156-
dc.relation.isPartOfCirculation Journal-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleCombined Algorithm Using a Poor Increase in Inferior P-Wave Amplitude During Sympathetic Stimulation and Sinus Node Recovery Time for the Diagnosis of Sick Sinus Syndrome-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorJin-Kyu Park-
dc.contributor.googleauthorJunbeom Park-
dc.contributor.googleauthorJae-Sun Uhm-
dc.contributor.googleauthorHui-Nam Pak-
dc.contributor.googleauthorMoon-Hyoung Lee-
dc.contributor.googleauthorBoyoung Joung-
dc.identifier.doi10.1253/circj.CJ-15-0561-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01776-
dc.contributor.localIdA02337-
dc.contributor.localIdA02766-
dc.contributor.localIdA03609-
dc.relation.journalcodeJ00534-
dc.contributor.alternativeNamePak, Hui Nam-
dc.contributor.alternativeNameUhm, Jae Sun-
dc.contributor.alternativeNameLee, Moon Hyoung-
dc.contributor.alternativeNameJoung, Bo Young-
dc.contributor.affiliatedAuthorPak, Hui Nam-
dc.contributor.affiliatedAuthorUhm, Jae Sun-
dc.contributor.affiliatedAuthorLee, Moon Hyoung-
dc.contributor.affiliatedAuthorJoung, Bo Young-
dc.rights.accessRightsfree-
dc.citation.volume79-
dc.citation.number10-
dc.citation.startPage2148-
dc.citation.endPage2156-
dc.identifier.bibliographicCitationCirculation Journal, Vol.79(10) : 2148-2156, 2015-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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