0 219

Cited 12 times in

The optimal serum pepsinogen cut-off value for predicting histologically confirmed atrophic gastritis

DC FieldValueLanguage
dc.contributor.author강화평-
dc.contributor.author김은혜-
dc.contributor.author박준철-
dc.contributor.author신성관-
dc.contributor.author이상길-
dc.contributor.author이용찬-
dc.contributor.author정다현-
dc.contributor.author정현수-
dc.contributor.author최희승-
dc.date.accessioned2016-02-04T11:48:12Z-
dc.date.available2016-02-04T11:48:12Z-
dc.date.issued2015-
dc.identifier.issn1590-8658-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/141237-
dc.description.abstractBACKGROUND: Although serum pepsinogen tests are useful for predicting the presence of atrophic gastritis, the optimal cut-off values have not been fully evaluated. AIM: To determine the optimal serum pepsinogen cut-off value for predicting atrophic gastritis. METHODS: Patients scheduled for upper endoscopy at Severance Hospital, Korea, between August 2012 and October 2013, were recruited prospectively. Endoscopic biopsies for atrophic gastritis were obtained and histologically graded, based on the updated Sydney system. RESULTS: Ninety-five patients were enrolled in the study. The mean age was 57.7±12.1 years, and 44.2% of the patients were male. Serum pepsinogen I/II ratios were lower in patients with atrophic gastritis than in those without it (antrum, 4.2±1.7 vs. 5.2±2.1, P=0.040; corpus, 3.3±1.9 vs. 5.4±1.9, P<0.001). Serum pepsinogen I/II ratios were significantly correlated with histologic atrophic gastritis (antrum, P=0.030; corpus, P<0.001). Using a cut-off value of 4.9, the sensitivity and specificity of the serum pepsinogen I/II ratio for predicting atrophic gastritis in the antrum were 68.2% and 60.3%, respectively. CONCLUSION: The optimal serum pepsinogen I/II ratio cut-off values for atrophic gastritis of the antrum and for the corpus were 4.9 and 3.5, respectively. Serum pepsinogen I/II ratios, with these cut-off values, are useful for screening patients for the presence of atrophic gastritis.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfDigestive and Liver Disease-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleThe optimal serum pepsinogen cut-off value for predicting histologically confirmed atrophic gastritis-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pathology (병리학)-
dc.contributor.googleauthorEun Hye Kim-
dc.contributor.googleauthorHuapyong Kang-
dc.contributor.googleauthorChan Hyuk Park-
dc.contributor.googleauthorHee Seung Choi-
dc.contributor.googleauthorDa Hyun Jung-
dc.contributor.googleauthorHyunsoo Chung-
dc.contributor.googleauthorJun Chul Park-
dc.contributor.googleauthorSung Kwan Shin-
dc.contributor.googleauthorSang Kil Lee-
dc.contributor.googleauthorYong Chan Lee-
dc.identifier.doi10.1016/j.dld.2015.05.014-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00100-
dc.contributor.localIdA01676-
dc.contributor.localIdA02112-
dc.contributor.localIdA02812-
dc.contributor.localIdA02988-
dc.contributor.localIdA03591-
dc.contributor.localIdA04229-
dc.contributor.localIdA00827-
dc.relation.journalcodeJ00735-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S1590865815003436-
dc.contributor.alternativeNameKang, Hwa Pyoung-
dc.contributor.alternativeNameKim, Eun Hye-
dc.contributor.alternativeNamePark, Jun Chul-
dc.contributor.alternativeNameShin, Sung Kwan-
dc.contributor.alternativeNameLee, Sang Kil-
dc.contributor.alternativeNameLee, Yong Chan-
dc.contributor.alternativeNameJung, Da Hyun-
dc.contributor.alternativeNameChung, Hyun Soo-
dc.contributor.alternativeNameChoi, Heeseung-
dc.contributor.affiliatedAuthorKang, Hwa Pyoung-
dc.contributor.affiliatedAuthorPark, Jun Chul-
dc.contributor.affiliatedAuthorShin, Sung Kwan-
dc.contributor.affiliatedAuthorLee, Sang Kil-
dc.contributor.affiliatedAuthorLee, Yong Chan-
dc.contributor.affiliatedAuthorJung, Da Hyun-
dc.contributor.affiliatedAuthorChoi, Heeseung-
dc.contributor.affiliatedAuthorKim, Eun Hye-
dc.rights.accessRightsnot free-
dc.citation.volume47-
dc.citation.number8-
dc.citation.startPage663-
dc.citation.endPage668-
dc.identifier.bibliographicCitationDigestive and Liver Disease, Vol.47(8) : 663-668, 2015-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.