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Clinical Characteristics and Treatment Outcomes of Cryptogenic Multifocal Ulcerous Stenosing Enteritis in Korea

DC FieldValueLanguage
dc.contributor.author정숙희-
dc.contributor.author천재희-
dc.date.accessioned2016-02-04T11:40:57Z-
dc.date.available2016-02-04T11:40:57Z-
dc.date.issued2015-
dc.identifier.issn0163-2116-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/140964-
dc.description.abstractBACKGROUND: Cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) is a rare disease that is characterized by multiple, recurring small intestinal ulcers with stenosis of unknown causes. The aim of this study was to investigate the clinical characteristics and the treatment outcomes of patients with CMUSE in Korea. METHODS: We performed a multicenter study to retrospectively analyze clinical data from 20 patients who suffered from CMUSE between 1984 and 2012. Their clinical characteristics and long-term disease courses were investigated. RESULTS: The most common initial symptom of CMUSE was abdominal pain (14/20, 70 %). Small bowel series (13/20, 65 %), double-balloon enteroscopy (12/20, 60 %), CT enterography (12/20, 60 %), and capsule endoscopy (10/20, 50 %) were used to diagnose CMUSE. The strictures of the patients were located in the jejunum (5/20, 25 %), ileum (7/20, 35 %), and both jejunum and ileum (6/20, 30 %). The number of patients in a state of remission, persistent disease, and relapse at the end of follow-up were 13/20 (65 %), 2/20 (10 %), and 5/20 (25 %), respectively. The median relapse-free survival was of 67.1 months. Seventy-five percent relapse-free survivals for female and male patients were 93 and 9 months, respectively (P = 0.031). CONCLUSION: CMUSE is difficult to diagnose and is an easily relapsing disease. Female patients might have a better prognosis than male patients in terms of the relapse-free time.-
dc.description.statementOfResponsibilityopen-
dc.format.extent2740~2745-
dc.relation.isPartOfDigestive Diseases and Sciences-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAbdominal Pain/etiology-
dc.subject.MESHAdult-
dc.subject.MESHConstriction, Pathologic/etiology-
dc.subject.MESHConstriction, Pathologic/pathology-
dc.subject.MESHConstriction, Pathologic/surgery-
dc.subject.MESHDisease-Free Survival-
dc.subject.MESHEndoscopy, Gastrointestinal-
dc.subject.MESHEnteritis/complications*-
dc.subject.MESHEnteritis/diagnosis-
dc.subject.MESHEnteritis/therapy-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHIleal Diseases/etiology*-
dc.subject.MESHIleal Diseases/pathology-
dc.subject.MESHIleal Diseases/therapy-
dc.subject.MESHJejunal Diseases/etiology*-
dc.subject.MESHJejunal Diseases/pathology-
dc.subject.MESHJejunal Diseases/therapy-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHRecurrence-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHUlcer/etiology*-
dc.subject.MESHUlcer/pathology-
dc.subject.MESHUlcer/therapy-
dc.titleClinical Characteristics and Treatment Outcomes of Cryptogenic Multifocal Ulcerous Stenosing Enteritis in Korea-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorSook Hee Chung-
dc.contributor.googleauthorSang Un Park-
dc.contributor.googleauthorJae Hee Cheon-
dc.contributor.googleauthorEun Ran Kim-
dc.contributor.googleauthorJeong-Sik Byeon-
dc.contributor.googleauthorByong Duk Ye-
dc.contributor.googleauthorBora Keum-
dc.contributor.googleauthorKi-Nam Shim-
dc.contributor.googleauthorSung-Ae Jung-
dc.contributor.googleauthorJin-Oh Kim-
dc.contributor.googleauthorSeong Ran Jeon-
dc.contributor.googleauthorHyun Joo Song-
dc.contributor.googleauthorJeong Seop Moon-
dc.contributor.googleauthorDong Kyung Chang-
dc.identifier.doi10.1007/s10620-015-3595-y-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03641-
dc.contributor.localIdA04030-
dc.relation.journalcodeJ00737-
dc.identifier.pmid25708899-
dc.identifier.urlhttp://link.springer.com/article/10.1007%2Fs10620-015-3595-y-
dc.subject.keywordCryptogenic multifocal ulcerous stenosing enteritis-
dc.subject.keywordDiagnosis-
dc.subject.keywordCharacteristics-
dc.subject.keywordTreatment outcome-
dc.contributor.alternativeNameChung, Sook Hee-
dc.contributor.alternativeNameCheon, Jae Hee-
dc.contributor.affiliatedAuthorChung, Sook Hee-
dc.contributor.affiliatedAuthorCheon, Jae Hee-
dc.rights.accessRightsnot free-
dc.citation.volume60-
dc.citation.number9-
dc.citation.startPage2740-
dc.citation.endPage2745-
dc.identifier.bibliographicCitationDigestive Diseases and Sciences, Vol.60(9) : 2740-2745, 2015-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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