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Characteristics of aortic valve dysfunction and ascending aorta dimensions according to bicuspid aortic valve morphology

 Hong Ju Shin  ;  Je Kyoun Shin  ;  Sung Min Ko  ;  Jun Suk Kim  ;  Hyun Kun Chee 
 EUROPEAN RADIOLOGY, Vol.25(7) : 2103-2014, 2015 
Journal Title
Issue Date
Aorta/pathology* ; Aorta/physiopathology ; Aortic Valve/abnormalities* ; Aortic Valve/pathology ; Aortic Valve/physiopathology ; Aortic Valve Insufficiency/pathology* ; Aortic Valve Insufficiency/physiopathology ; Aortic Valve Stenosis/diagnostic imaging ; Aortic Valve Stenosis/pathology* ; Aortic Valve Stenosis/physiopathology ; Body Surface Area ; Dilatation, Pathologic/pathology ; Dilatation, Pathologic/physiopathology ; Echocardiography ; Electrocardiography ; Female ; Heart Valve Diseases/pathology* ; Heart Valve Diseases/physiopathology ; Humans ; Male ; Middle Aged ; Multimodal Imaging ; Retrospective Studies ; Tomography, X-Ray Computed
Computed tomography ; Transthoracic echocardiography ; Bicuspid aortic valve ; Aortic stenosis ; Aortic regurgitation
OBJECTIVE: To characterize aortic valve dysfunction and ascending aorta dimensions according to bicuspid aortic valve (BAV) morphology using computed tomography (CT) and surgical findings. METHODS: We retrospectively enrolled 209 patients with BAVs who underwent transthoracic echocardiography (TTE) and CT. BAVs were classified as anterior-posterior (BAV-AP) or lateral (BAV-LA) orientation of the cusps and divided according to the presence (raphe+) or absence (raphe-) of a raphe. Ascending aortic dimensions were measured by CT at four levels. RESULTS: BAV-AP was present in 129 patients (61.7%) and raphe+ in 120 (57.4%). Sixty-nine patients (33.0%) had aortic regurgitation (AR), 70 (33.5%) had aortic stenosis (AS), and 58 (27.8%) had combined AS and AR. AR was more common in patients with BAV-AP and raphe+; AS was more common with BAV-LA and raphe-.Annulus/body surface area and tubular portion/body surface area diameters in patients with BAV-AP (17.1 ± 2.3 mm/m(2) and 24.2 ± 5.3 mm/m(2), respectively) and raphe+ (17.3 ± 2.2 mm/m(2) and 24.2 ± 5.5 mm/m(2), respectively) were significantly different from those with BAV-LA (15.8 ± 1.9 mm/m(2) and 26.4 ± 5.5 mm/m(2), respectively) and raphe- (15.7 ± 1.9 mm/m(2) and 26.2 ± 5.4 mm/m(2), respectively). CONCLUSION: The morphological characteristics of BAV might be associated with the type of valvular dysfunction, and degree and location of an ascending aorta dilatation. KEY POINTS: • The BAV-AP type had more frequent aortic regurgitation, raphe, and a larger aortic annulus. • BAV without raphe had more frequent aortic stenosis and mid-ascending aorta dilatation. • CT allows assessment of the morphological characteristics of BAV and associated aortopathy.
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1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
Yonsei Authors
Shin, Hong Ju(신홍주)
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