Cited 11 times in
Capillary-scale direct measurement of hemoglobin concentration of erythrocytes using photothermal angular light scattering
DC Field | Value | Language |
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dc.contributor.author | 송재우 | - |
dc.date.accessioned | 2016-02-04T11:37:53Z | - |
dc.date.available | 2016-02-04T11:37:53Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 0956-5663 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/140851 | - |
dc.description.abstract | We present a direct, rapid and chemical-free detection method for hemoglobin concentration ([Hb]), based on photothermal angular light scattering. The iron oxides contained in hemoglobin molecules exhibit high absorption of 532-nm light and generate heat under the illumination of 532-nm light, which subsequently alters the refractive index of blood. We measured this photothermal change in refractive index by employing angular light scattering spectroscopy with the goal of quantifying [Hb] in blood samples. Highly sensitive [Hb] measurement of blood samples was performed by monitoring the shifts in angularly dispersed scattering patterns from the blood-loaded microcapillary tubes. Our system measured [Hb] over the range of 0.35-17.9 g/dL with a detection limit of ~0.12 g/dL. Our sensor was characterized by excellent correlation with a reference hematology analyzer (r>0.96), and yielded a precision of 0.63 g/dL for a blood sample of 9.0 g/dL. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 469~475 | - |
dc.relation.isPartOf | BIOSENSORS & BIOELECTRONICS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Biosensing Techniques/instrumentation* | - |
dc.subject.MESH | Equipment Design | - |
dc.subject.MESH | Equipment Failure Analysis | - |
dc.subject.MESH | Erythrocytes/metabolism* | - |
dc.subject.MESH | Hemoglobins/metabolism* | - |
dc.subject.MESH | Hot Temperature | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Light | - |
dc.subject.MESH | Lighting/instrumentation* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Refractometry/instrumentation* | - |
dc.subject.MESH | Reproducibility of Results | - |
dc.subject.MESH | Scattering, Radiation | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.subject.MESH | Young Adult | - |
dc.title | Capillary-scale direct measurement of hemoglobin concentration of erythrocytes using photothermal angular light scattering | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학) | - |
dc.contributor.googleauthor | Uihan Kim | - |
dc.contributor.googleauthor | Jaewoo Song | - |
dc.contributor.googleauthor | Donghak Lee | - |
dc.contributor.googleauthor | Suho Ryu | - |
dc.contributor.googleauthor | Soocheol Kim | - |
dc.contributor.googleauthor | Jaehyun Hwang | - |
dc.contributor.googleauthor | Chulmin Joo | - |
dc.identifier.doi | 10.1016/j.bios.2015.06.066 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02054 | - |
dc.relation.journalcode | J00330 | - |
dc.identifier.eissn | 1873-4235 | - |
dc.identifier.pmid | 26176206 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0956566315302347 | - |
dc.subject.keyword | Angular light scattering | - |
dc.subject.keyword | Erythrocytes | - |
dc.subject.keyword | Hemoglobin | - |
dc.subject.keyword | Hemoglobin concentration | - |
dc.subject.keyword | Photothermal effect | - |
dc.subject.keyword | Refractive index | - |
dc.contributor.alternativeName | Song, Jae Woo | - |
dc.contributor.affiliatedAuthor | Song, Jae Woo | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 74 | - |
dc.citation.startPage | 469 | - |
dc.citation.endPage | 475 | - |
dc.identifier.bibliographicCitation | BIOSENSORS & BIOELECTRONICS, Vol.74 : 469-475, 2015 | - |
dc.identifier.rimsid | 30350 | - |
dc.type.rims | ART | - |
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