374 267

Cited 26 times in

A network meta-analysis of therapeutic outcomes after new image technology-assisted transurethral resection for non-muscle invasive bladder cancer: 5-aminolaevulinic acid fluorescence vs hexylaminolevulinate fluorescence vs narrow band imaging

DC FieldValueLanguage
dc.contributor.author이주용-
dc.contributor.author정해도-
dc.contributor.author조강수-
dc.contributor.author최영득-
dc.contributor.author함원식-
dc.contributor.author권종규-
dc.date.accessioned2016-02-04T11:35:58Z-
dc.date.available2016-02-04T11:35:58Z-
dc.date.issued2015-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/140781-
dc.description.abstractBACKGROUND: This study included a network meta-analysis of evidence from randomized controlled trials (RCTs) to assess the therapeutic outcome of transurethral resection (TUR) in patients with non-muscle-invasive bladder cancer assisted by photodynamic diagnosis (PDD) employing 5-aminolaevulinic acid (5-ALA) or hexylaminolevulinate (HAL) or by narrow band imaging (NBI). METHODS: Relevant RCTs were identified from electronic databases. The proceedings of relevant congresses were also searched. Fifteen articles based on RCTs were included in the analysis, and the comparisons were made by qualitative and quantitative syntheses using pairwise and network meta-analyses. RESULTS: Seven of 15 RCTs were at moderate risk of bias for all quality criteria and two studies were classified as having a high risk of bias. The recurrence rate of cancers resected with 5-ALA-based PDD was lower than of those resected using HAL-based PDD (odds ratio (OR) = 0.48, 95 % confidence interval (CI) [0.26-0.95]) but was not significantly different than those resected with NBI (OR = 0.53, 95 % CI [0.26-1.09]). The recurrence rate of cancers resected using HAL-based PDD versus NBI did not significantly differ (OR = 1.11, 95 % CI [0.55-2.1]). All cancers resected using 5-ALA-based PDD, HAL-based PDD, or NBI recurred at a lower rate than those resected using white light cystoscopy (WLC). No difference in progression rate was observed between cancers resected by all methods investigated. CONCLUSIONS: The recurrence rate of some bladder cancers can be decreased by the implementation of either PDD- and NBI-assisted TUR; in real settings, clinicians should consider replacing WLC as the standard imaging technology to guide TUR.-
dc.description.statementOfResponsibilityopen-
dc.format.extent566-
dc.relation.isPartOfBMC CANCER-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAminolevulinic Acid/analogs & derivatives*-
dc.subject.MESHAminolevulinic Acid/metabolism*-
dc.subject.MESHCystoscopy/methods-
dc.subject.MESHHumans-
dc.subject.MESHImage Interpretation, Computer-Assisted/methods*-
dc.subject.MESHNarrow Band Imaging/methods-
dc.subject.MESHPhotosensitizing Agents/metabolism*-
dc.subject.MESHRandomized Controlled Trials as Topic-
dc.subject.MESHTreatment Outcome-
dc.subject.MESHUrinary Bladder Neoplasms/metabolism-
dc.subject.MESHUrinary Bladder Neoplasms/pathology-
dc.subject.MESHUrinary Bladder Neoplasms/surgery*-
dc.titleA network meta-analysis of therapeutic outcomes after new image technology-assisted transurethral resection for non-muscle invasive bladder cancer: 5-aminolaevulinic acid fluorescence vs hexylaminolevulinate fluorescence vs narrow band imaging-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Urology (비뇨기과학)-
dc.contributor.googleauthorJoo Yong Lee-
dc.contributor.googleauthorKang Su Cho-
dc.contributor.googleauthorDong Hyuk Kang-
dc.contributor.googleauthorHae Do Jung-
dc.contributor.googleauthorJong Kyou Kwon-
dc.contributor.googleauthorCheol Kyu Oh-
dc.contributor.googleauthorWon Sik Ham-
dc.contributor.googleauthorYoung Deuk Choi-
dc.identifier.doi10.1186/s12885-015-1571-8-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03161-
dc.contributor.localIdA03759-
dc.contributor.localIdA03801-
dc.contributor.localIdA04111-
dc.contributor.localIdA04337-
dc.contributor.localIdA00250-
dc.relation.journalcodeJ00351-
dc.identifier.eissn1471-2407-
dc.identifier.pmid26232037-
dc.subject.keywordUrinary bladder neoplasms-
dc.subject.keywordPhotochemotherapy-
dc.subject.keywordNarrow band imaging-
dc.subject.keywordMeta-analysis-
dc.subject.keywordBayes theorem-
dc.contributor.alternativeNameLee, Joo Yong-
dc.contributor.alternativeNameJung, Hae Do-
dc.contributor.alternativeNameCho, Kang Su-
dc.contributor.alternativeNameChoi, Young Deuk-
dc.contributor.alternativeNameHam, Won Sik-
dc.contributor.alternativeNameKwon, Jong Kyou-
dc.contributor.affiliatedAuthorLee, Joo Yong-
dc.contributor.affiliatedAuthorJung, Hae Do-
dc.contributor.affiliatedAuthorCho, Kang Su-
dc.contributor.affiliatedAuthorChoi, Young Deuk-
dc.contributor.affiliatedAuthorHam, Won Sik-
dc.contributor.affiliatedAuthorKwon, Jong Kyou-
dc.rights.accessRightsfree-
dc.citation.volume15-
dc.citation.startPage566-
dc.identifier.bibliographicCitationBMC CANCER, Vol.15 : 566, 2015-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
7. Others (기타) > Dept. of Health Promotion (건강의학과) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.