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Methotrexate-induced Oral Mucositis

DC FieldValueLanguage
dc.contributor.author권정승-
dc.contributor.author안형준-
dc.contributor.author최영찬-
dc.date.accessioned2016-02-04T11:34:57Z-
dc.date.available2016-02-04T11:34:57Z-
dc.date.issued2015-
dc.identifier.issn2288-9272-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/140745-
dc.description.abstractMethotrexate (MTX) is a chemotherapeutic agent that is used to treat a host of malignancies. But recently, MTX has also been used as a therapeutic agent for chronic inflammatory disorders such as rheumatoid arthritis, psoriasis, and systemic lupus erythematosus. However, MTX is an antimetabolite that affects rapidly dividing normal cells such as oral mucosal epithelial cells, gastrointestinal epithelial cells, and bone marrow cells?which explains why oral mucositis is often an initial manifestation of MTX toxicity. Because oral lesions are frequently initially presented in dental clinics, dentists should consider the possibility of adverse drug reactions in the differential diagnoses of oral lesions through a meticulous collection of patients’ medical histories. In this report, we examine patients who suffered from oral ulcerative lesions upon diagnosis of MTX-induced oral mucositis. Then, we suggest approaches for the diagnosis and treatment of MTX-induced oral mucositis through a review of literature.-
dc.description.statementOfResponsibilityopen-
dc.format.extent82~87-
dc.relation.isPartOfJournal of Oral Medicine and Pain-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleMethotrexate-induced Oral Mucositis-
dc.typeArticle-
dc.contributor.collegeCollege of Dentistry (치과대학)-
dc.contributor.departmentDept. of Oral Medicine (구강내과학)-
dc.contributor.googleauthorHye Jin Lee-
dc.contributor.googleauthorJeong Seung Kwon-
dc.contributor.googleauthorYoung Chan Choi-
dc.contributor.googleauthorHyung Joon Ahn-
dc.identifier.doi10.14476/jomp.2015.40.2.82-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00249-
dc.contributor.localIdA02273-
dc.contributor.localIdA04115-
dc.relation.journalcodeJ01664-
dc.subject.keywordFolic acid deficiency-
dc.subject.keywordMethotrexate-
dc.subject.keywordOral mucositis-
dc.subject.keywordRheumatoid arthritis-
dc.contributor.alternativeNameKwon, Jeong Seung-
dc.contributor.alternativeNameAhn, Hyoung Joon-
dc.contributor.alternativeNameChoi, Young Chan-
dc.contributor.affiliatedAuthorKwon, Jeong Seung-
dc.contributor.affiliatedAuthorAhn, Hyoung Joon-
dc.contributor.affiliatedAuthorChoi, Young Chan-
dc.rights.accessRightsfree-
dc.citation.volume40-
dc.citation.number2-
dc.citation.startPage82-
dc.citation.endPage87-
dc.identifier.bibliographicCitationJournal of Oral Medicine and Pain, Vol.40(2) : 82-87, 2015-
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Orofacial Pain and Oral Medicine (구강내과학교실) > 1. Journal Papers

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