Cited 21 times in
In vitro activity of tedizolid against gram-positive bacteria in patients with skin and skin structure infections and hospital-acquired pneumonia: a Korean multicenter study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 용동은 | - |
dc.contributor.author | 이경원 | - |
dc.date.accessioned | 2016-02-04T11:34:15Z | - |
dc.date.available | 2016-02-04T11:34:15Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 2234-3806 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/140720 | - |
dc.description.abstract | We compared the activities of tedizolid to those of linezolid and other commonly used antimicrobial agents against gram-positive cocci recovered from patients with skin and skin structure infections (SSSIs) and hospital-acquired pneumonia (HAP) in Korean hospitals. Gram-positive isolates were collected from 356 patients with SSSIs and 144 patients with HAP at eight hospitals in Korea from 2011 to 2014. SSSIs included impetigo, cellulitis, erysipelas, furuncles, abscesses, and infected burns. Antimicrobial susceptibility was tested by using the CLSI agar dilution method. All of the gram-positive isolates were inhibited by ≤1 μg/mL tedizolid. The minimum inhibitory concentration [MIC]₉₀ of tedizolid was 0.5 μg/mL for methicillin-resistant Staphylococcus aureus, which was 4-fold lower than that of linezolid. Tedizolid may become a useful option for the treatment of SSSIs and HAP caused by gram-positive bacteria. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 523~530 | - |
dc.relation.isPartOf | ANNALS OF LABORATORY MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Anti-Bacterial Agents/pharmacology* | - |
dc.subject.MESH | Asian Continental Ancestry Group | - |
dc.subject.MESH | Gram-Positive Bacteria/drug effects* | - |
dc.subject.MESH | Gram-Positive Bacteria/isolation & purification | - |
dc.subject.MESH | Gram-Positive Bacterial Infections/diagnosis | - |
dc.subject.MESH | Gram-Positive Bacterial Infections/microbiology | - |
dc.subject.MESH | Hospitals | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Linezolid/pharmacology | - |
dc.subject.MESH | Methicillin-Resistant Staphylococcus aureus/drug effects | - |
dc.subject.MESH | Microbial Sensitivity Tests | - |
dc.subject.MESH | Organophosphates/pharmacology* | - |
dc.subject.MESH | Oxazoles/pharmacology* | - |
dc.subject.MESH | Pneumonia/diagnosis | - |
dc.subject.MESH | Pneumonia/microbiology* | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Skin/microbiology* | - |
dc.subject.MESH | Skin Diseases/diagnosis | - |
dc.subject.MESH | Skin Diseases/microbiology* | - |
dc.title | In vitro activity of tedizolid against gram-positive bacteria in patients with skin and skin structure infections and hospital-acquired pneumonia: a Korean multicenter study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학) | - |
dc.contributor.googleauthor | Yangsoon Lee | - |
dc.contributor.googleauthor | Sung Kuk Hong | - |
dc.contributor.googleauthor | SungHak Choi | - |
dc.contributor.googleauthor | Weonbin Im | - |
dc.contributor.googleauthor | Dongeun Yong | - |
dc.contributor.googleauthor | Kyungwon Lee | - |
dc.identifier.doi | 10.3343/alm.2015.35.5.523 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02423 | - |
dc.contributor.localId | A02649 | - |
dc.relation.journalcode | J00164 | - |
dc.identifier.eissn | 2234-3814 | - |
dc.identifier.pmid | 26206690 | - |
dc.subject.keyword | Gram-positive bacteria | - |
dc.subject.keyword | Infection | - |
dc.subject.keyword | Pneumonia | - |
dc.subject.keyword | Skin | - |
dc.subject.keyword | Soft tissue | - |
dc.subject.keyword | Tedizolid | - |
dc.contributor.alternativeName | Yong, Dong Eun | - |
dc.contributor.alternativeName | Lee, Kyung Won | - |
dc.contributor.affiliatedAuthor | Yong, Dong Eun | - |
dc.contributor.affiliatedAuthor | Lee, Kyung Won | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 35 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 523 | - |
dc.citation.endPage | 530 | - |
dc.identifier.bibliographicCitation | ANNALS OF LABORATORY MEDICINE, Vol.35(5) : 523-530, 2015 | - |
dc.identifier.rimsid | 30266 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.