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Three-Dimensional Echocardiographic Evaluation of Mitral Apparatus during Preload Manipulation in Patients with Hypertrophic Cardiomyopathy

DC FieldValueLanguage
dc.contributor.author정혜문-
dc.contributor.author최의영-
dc.contributor.author홍범기-
dc.contributor.author권혁문-
dc.contributor.author김종윤-
dc.contributor.author민필기-
dc.contributor.author윤영원-
dc.contributor.author윤지현-
dc.contributor.author이병권-
dc.contributor.author임세중-
dc.contributor.author차정준-
dc.date.accessioned2016-02-04T11:33:55Z-
dc.date.available2016-02-04T11:33:55Z-
dc.date.issued2015-
dc.identifier.issn0742-2822-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/140708-
dc.description.abstractBACKGROUND: The three-dimensional (3D) dynamic change of mitral geometry during preload manipulation has not been fully investigated. We investigated how preload manipulation affected the mitral apparatus geometry in hypertrophic cardiomyopathy (HCM) patients using 3D echocardiography. METHODS AND RESULTS: Twenty five HCM patients, thirteen with obstructive HCM (HOCM) and twelve with nonobstructive HCM (HNCM), and six healthy controls were studied. Subjects underwent 3D echocardiography during rest, leg raising, the Valsalva maneuver, and the Valsalva maneuver after nitroglycerin intake (NTG-Valsalva). Left ventricular outflow tract (LVOT) pressure gradients, mitral annular area, annular circumference, and the tenting volume of the mitral leaflets were measured. Standardized annular area significantly decreased during the NTG-Valsalva maneuver in all 3 groups (▵2.23 mm(2) /m(2) in control, P = 0.031; ▵0.46 mm(2) /m(2) in HNCM, P = 0.012; ▵1.3 mm(2) /m(2) in HOCM, P = 0.013). Standardized annular area decrease during the Valsalva maneuver alone was more prominent in HNCM patients (▵0.57 mm(2) /m(2) , P = 0.009) than HOCM patients (▵0.3 mm(2) /m(2) , P = 0.094). Standardized mitral tenting volume during the NTG-Valsalva maneuver significantly decreased only in HOCM patients (▵1.18 mm(3) /m(2) , P = 0.046). CONCLUSION: Decreased mitral annular area and changes in leaflets tenting volume during preload reduction might affect the development of LVOT obstruction. Our data suggest the importance of preserving the saddle-shaped of the mitral annulus in management of HCM with LVOT obstruction.-
dc.description.statementOfResponsibilityopen-
dc.format.extent1261~1269-
dc.relation.isPartOfEchocardiography-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleThree-Dimensional Echocardiographic Evaluation of Mitral Apparatus during Preload Manipulation in Patients with Hypertrophic Cardiomyopathy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorHyemoon Chung-
dc.contributor.googleauthorJi Hyun Yoon-
dc.contributor.googleauthorYoung Won Yoon-
dc.contributor.googleauthorJi Young Chung-
dc.contributor.googleauthorJung-Joon Cha-
dc.contributor.googleauthorJong-Youn Kim-
dc.contributor.googleauthorPil-Ki Min-
dc.contributor.googleauthorByoung-Kwon Lee-
dc.contributor.googleauthorBum-Kee Hong-
dc.contributor.googleauthorSe-Joong Rim-
dc.contributor.googleauthorHyuck Moon Kwon-
dc.contributor.googleauthorEui-Young Choi-
dc.identifier.doi10.1111/echo.12840-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03779-
dc.contributor.localIdA04165-
dc.contributor.localIdA04394-
dc.contributor.localIdA00260-
dc.contributor.localIdA00926-
dc.contributor.localIdA01412-
dc.contributor.localIdA02580-
dc.contributor.localIdA02609-
dc.contributor.localIdA02793-
dc.contributor.localIdA03372-
dc.contributor.localIdA04851-
dc.relation.journalcodeJ00756-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1111/echo.12840/abstract-
dc.contributor.alternativeNameChung, Hye Moon-
dc.contributor.alternativeNameChoi, Eui Young-
dc.contributor.alternativeNameHong, Bum Kee-
dc.contributor.alternativeNameKwon, Hyuck Moon-
dc.contributor.alternativeNameKim, Jong Youn-
dc.contributor.alternativeNameMin, Pil Ki-
dc.contributor.alternativeNameYoon, Young Won-
dc.contributor.alternativeNameYoon, Ji Hyun-
dc.contributor.alternativeNameLee, Byoung Kwon-
dc.contributor.alternativeNameRim, Se Joong-
dc.contributor.affiliatedAuthorChung, Hye Moon-
dc.contributor.affiliatedAuthorChoi, Eui Young-
dc.contributor.affiliatedAuthorHong, Bum Kee-
dc.contributor.affiliatedAuthorKwon, Hyuck Moon-
dc.contributor.affiliatedAuthorKim, Jong Youn-
dc.contributor.affiliatedAuthorMin, Pil Ki-
dc.contributor.affiliatedAuthorYoon, Young Won-
dc.contributor.affiliatedAuthorYoon, Ji Hyun-
dc.contributor.affiliatedAuthorLee, Byoung Kwon-
dc.contributor.affiliatedAuthorRim, Se Joong-
dc.contributor.affiliatedAuthorCha, Jung Joon-
dc.rights.accessRightsnot free-
dc.citation.volume32-
dc.citation.number8-
dc.citation.startPage1261-
dc.citation.endPage1269-
dc.identifier.bibliographicCitationEchocardiography, Vol.32(8) : 1261-1269, 2015-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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