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Usefulness of maternal serum C-reactive protein with vaginal Ureaplasma urealyticum as a marker for prediction of imminent preterm delivery and chorioamnionitis in patients with preterm labor or preterm premature rupture of membranes

DC FieldValueLanguage
dc.contributor.author권자영-
dc.contributor.author김영한-
dc.contributor.author박용원-
dc.contributor.author조희영-
dc.date.accessioned2016-02-04T11:32:59Z-
dc.date.available2016-02-04T11:32:59Z-
dc.date.issued2015-
dc.identifier.issn0300-5577-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/140674-
dc.description.abstractAIM: To assess whether maternal serum C-reactive protein (CRP) and genital mycoplasmas measured can help predict imminent preterm delivery or chorioamnionitis in patients with preterm labor (PL) or preterm premature rupture of membranes (PPROM). METHODS: The study group consisted of 165 women with PL or PPROM. Vaginal cultures for genital mycoplasmas and maternal blood for CRP were obtained when they were admitted for the management of PL or PPROM. An elevated level of serum CRP was defined as ≥0.8 mg/dL. Histologic evaluation of the placenta was performed after delivery. RESULTS: The prevalence of positive vaginal fluid cultures for Ureaplasma urealyticum (UU) was 63.0%, and elevated maternal serum CRP was 32.7%. No outcome variables were associated with vaginal UU infection in patients with lower CRP levels. However, among women with elevated CRP, the mean gestational age at birth was significantly reduced, and low Apgar score, neonatal intensive care unit admission, histologic chorioamnionitis, and delivery within 7 days of admission were significantly more common in patients with vaginal UU. CONCLUSIONS: Although vaginal UU in PL or PPROM cannot act as the sole predictor of imminent preterm delivery or chorioamnionitis, it can provide predictive information in patients with elevated maternal serum CRP levels.-
dc.description.statementOfResponsibilityopen-
dc.format.extent409~415-
dc.relation.isPartOfJournal of Perinatal Medicine-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHBiomarkers-
dc.subject.MESHC-Reactive Protein/metabolism*-
dc.subject.MESHChorioamnionitis/blood-
dc.subject.MESHChorioamnionitis/diagnosis*-
dc.subject.MESHChorioamnionitis/microbiology-
dc.subject.MESHFemale-
dc.subject.MESHFetal Membranes, Premature Rupture/blood*-
dc.subject.MESHFetal Membranes, Premature Rupture/microbiology-
dc.subject.MESHHumans-
dc.subject.MESHPredictive Value of Tests-
dc.subject.MESHPregnancy-
dc.subject.MESHPregnancy Outcome-
dc.subject.MESHPremature Birth/blood*-
dc.subject.MESHPremature Birth/microbiology-
dc.subject.MESHUreaplasma urealyticum/isolation & purification*-
dc.subject.MESHVaginal Smears-
dc.titleUsefulness of maternal serum C-reactive protein with vaginal Ureaplasma urealyticum as a marker for prediction of imminent preterm delivery and chorioamnionitis in patients with preterm labor or preterm premature rupture of membranes-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Obstetrics & Gynecology (산부인과학)-
dc.contributor.googleauthorDong Wook Kwak-
dc.contributor.googleauthorHee Young Cho-
dc.contributor.googleauthorJa Young Kwon-
dc.contributor.googleauthorYong Won Park-
dc.contributor.googleauthorYoung Han Kim-
dc.identifier.doi10.1515/jpm-2014-0142-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00246-
dc.contributor.localIdA00730-
dc.contributor.localIdA01581-
dc.contributor.localIdA03944-
dc.relation.journalcodeJ01693-
dc.identifier.pmid25503859-
dc.identifier.urlhttp://web.b.ebscohost.com/ehost/pdfviewer/pdfviewer?sid=fa292c2e-9b91-41aa-977d-55da3a9ce637%40sessionmgr112&vid=1&hid=116-
dc.subject.keywordC-reactive protein (CRP)-
dc.subject.keywordchorioamnionitis-
dc.subject.keywordgenital mycoplasma-
dc.subject.keywordpreterm labor (PL)-
dc.subject.keywordpreterm premature rupture of membranes (PPROM)-
dc.contributor.alternativeNameKwon, Ja Young-
dc.contributor.alternativeNameKim, Young Han-
dc.contributor.alternativeNamePark, Yong Won-
dc.contributor.alternativeNameCho, Hee Young-
dc.contributor.affiliatedAuthorKwon, Ja Young-
dc.contributor.affiliatedAuthorKim, Young Han-
dc.contributor.affiliatedAuthorPark, Yong Won-
dc.contributor.affiliatedAuthorCho, Hee Young-
dc.rights.accessRightsnot free-
dc.citation.volume43-
dc.citation.number4-
dc.citation.startPage409-
dc.citation.endPage415-
dc.identifier.bibliographicCitationJournal of Perinatal Medicine, Vol.43(4) : 409-415, 2015-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers

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