Cited 15 times in
Diagnostic utility of interferon-gamma release assay in extrapulmonary tuberculosis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 장윤수 | - |
dc.contributor.author | 김형중 | - |
dc.contributor.author | 변민광 | - |
dc.contributor.author | 안철민 | - |
dc.date.accessioned | 2016-02-04T11:30:18Z | - |
dc.date.available | 2016-02-04T11:30:18Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 0732-8893 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/140574 | - |
dc.description.abstract | Early diagnosis of extrapulmonary tuberculosis (EP-TB) is essential. However, diagnosis of EP-TB is difficult. We evaluated the diagnostic utility of an interferon-gamma release assay (IGRA) in diagnosing active EP-TB among suspected patients in Korea. We retrospectively reviewed the clinical records of all patients with suspected EP-TB at Gangnam Severance Hospital in Seoul, Korea. Of the 418 patients with suspected EP-TB, 324 had active EP-TB. The tuberculosis (TB) group had a higher percentage of positive IGRAs (70.2%, 33/47) than the non-TB group (33.3%, 3/9) (P=0.034). The IGRA sensitivity and specificity were 70.2% (63.7-74.8%) and 66.7% (32.9-90.6%), respectively. The sensitivity and specificity of IGRAs in patients with TB lymphadenitis were 81.8% (61.4-90.4%) and 80.0% (35.1-98.9%), but 38.5% (31.2-45.7%) and 50.0% (2.7-97.3%) in patients with TB pleurisy. The diagnostic performance of IGRAs may vary depending on the site of EP-TB involvement. IGRA was potentially valuable for diagnosis of active EP-TB in TB lymphadenopathy. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Diagnostic Tests, Routine/methods* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Interferon-gamma Release Tests/methods* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.subject.MESH | Seoul | - |
dc.subject.MESH | Tuberculosis/diagnosis* | - |
dc.subject.MESH | Young Adult | - |
dc.title | Diagnostic utility of interferon-gamma release assay in extrapulmonary tuberculosis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Jung Ar Shin | - |
dc.contributor.googleauthor | Yoon Soo Chang | - |
dc.contributor.googleauthor | Hyung Jung Kim | - |
dc.contributor.googleauthor | Chul Min Ahn | - |
dc.contributor.googleauthor | Min Kwang Byun | - |
dc.identifier.doi | 10.1016/j.diagmicrobio.2015.02.002 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03456 | - |
dc.contributor.localId | A01158 | - |
dc.contributor.localId | A01848 | - |
dc.contributor.localId | A02269 | - |
dc.relation.journalcode | J00731 | - |
dc.identifier.eissn | 1879-0070 | - |
dc.identifier.pmid | 25724852 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S073288931500036X | - |
dc.subject.keyword | Diagnosis | - |
dc.subject.keyword | Interferon-gamma | - |
dc.subject.keyword | Lymphadenitis | - |
dc.subject.keyword | Pleurisy | - |
dc.subject.keyword | Tuberculosis | - |
dc.contributor.alternativeName | Chang, Yoon Soo | - |
dc.contributor.alternativeName | Kim, Hyung Jung | - |
dc.contributor.alternativeName | Byun, Min Kwang | - |
dc.contributor.alternativeName | Ahn, Chul Min | - |
dc.contributor.affiliatedAuthor | Chang, Yoon Soo | - |
dc.contributor.affiliatedAuthor | Kim, Hyung Jung | - |
dc.contributor.affiliatedAuthor | Byun, Min Kwang | - |
dc.contributor.affiliatedAuthor | Ahn, Chul Min | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 82 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 44 | - |
dc.citation.endPage | 48 | - |
dc.identifier.bibliographicCitation | DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, Vol.82(1) : 44-48, 2015 | - |
dc.identifier.rimsid | 30180 | - |
dc.type.rims | ART | - |
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