Cited 194 times in
Epidemiology and Characteristics of Metallo-β-Lactamase-Producing Pseudomonas aeruginosa
DC Field | Value | Language |
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dc.contributor.author | 이경원 | - |
dc.contributor.author | 정석훈 | - |
dc.contributor.author | 홍덕진 | - |
dc.date.accessioned | 2016-02-04T11:30:05Z | - |
dc.date.available | 2016-02-04T11:30:05Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 2093-2340 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/140565 | - |
dc.description.abstract | Metallo-β-lactamase-producing Pseudomonas aeruginosa (MPPA) is an important nosocomial pathogen that shows resistance to all β-lactam antibiotics except monobactams. There are various types of metallo-β-lactamases (MBLs) in carbapenem-resistant P. aeruginosa including Imipenemase (IMP), Verona integron-encoded metallo-β-lactamase (VIM), Sao Paulo metallo-β-lactamase (SPM), Germany imipenemase (GIM), New Delhi metallo-β-lactamase (NDM), Florence imipenemase (FIM). Each MBL gene is located on specific genetic elements including integrons, transposons, plasmids, or on the chromosome, in which they carry genes encoding determinants of resistance to carbapenems and other antibiotics, conferring multidrug resistance to P. aeruginosa. In addition, these genetic elements are transferable to other Gram-negative species, increasing the antimicrobial resistance rate and complicating the treatment of infected patients. Therefore, it is essential to understand the epidemiology, resistance mechanism, and molecular characteristics of MPPA for infection control and prevention of a possible global health crisis. Here, we highlight the characteristics of MPPA. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 81~97 | - |
dc.relation.isPartOf | INFECTION AND CHEMOTHERAPY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Epidemiology and Characteristics of Metallo-β-Lactamase-Producing Pseudomonas aeruginosa | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학) | - |
dc.contributor.googleauthor | Duck Jin Hong | - |
dc.contributor.googleauthor | Il Kwon Bae | - |
dc.contributor.googleauthor | In-Ho Jang | - |
dc.contributor.googleauthor | Seok Hoon Jeong | - |
dc.contributor.googleauthor | Hyun-Kyung Kang | - |
dc.contributor.googleauthor | Kyungwon Lee | - |
dc.identifier.doi | 10.3947/ic.2015.47.2.81 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02649 | - |
dc.contributor.localId | A03619 | - |
dc.contributor.localId | A04389 | - |
dc.relation.journalcode | J01053 | - |
dc.identifier.eissn | 2092-6448 | - |
dc.identifier.pmid | 26157586 | - |
dc.subject.keyword | Carbapenem | - |
dc.subject.keyword | Epidemiology | - |
dc.subject.keyword | Metallo-β-lactamase | - |
dc.subject.keyword | Multidrug resistance | - |
dc.subject.keyword | Pseudomonas aeruginosa | - |
dc.contributor.alternativeName | Lee, Kyung Won | - |
dc.contributor.alternativeName | Jeong, Seok Hoon | - |
dc.contributor.alternativeName | Hong, Duck Jin | - |
dc.contributor.affiliatedAuthor | Lee, Kyung Won | - |
dc.contributor.affiliatedAuthor | Jeong, Seok Hoon | - |
dc.contributor.affiliatedAuthor | Hong, Duck Jin | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 47 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 81 | - |
dc.citation.endPage | 97 | - |
dc.identifier.bibliographicCitation | INFECTION AND CHEMOTHERAPY, Vol.47(2) : 81-97, 2015 | - |
dc.identifier.rimsid | 30176 | - |
dc.type.rims | ART | - |
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