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The Effect of 1 µg/kg Dexmedetomidine Combined with High-Volume/Low-Concentration Caudal Ropivacaine in Children Undergoing Ambulatory Orchiopexy

DC FieldValueLanguage
dc.contributor.author길혜금-
dc.contributor.author김지영-
dc.date.accessioned2016-02-04T11:29:57Z-
dc.date.available2016-02-04T11:29:57Z-
dc.date.issued2015-
dc.identifier.issn0918-6158-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/140560-
dc.description.abstractWhen local anesthetics are used, the administration of dexmedetomidine (DEX) can prolong analgesic duration. However, the effect of caudal DEX on high volume/low concentration (HVLC) local anesthetics has not been studied. We investigated the analgesic effect of DEX added to a HVLC of ropivacaine for caudal block in children. Eighty children (the American Society of Anesthesiologists (ASA) status I; age, 1-6 years) undergoing ambulatory orchiopexy were enrolled in the study. Children were randomly assigned to undergo a caudal block with 1.5 mL/kg of 0.15% ropivacaine and either 1 µg/kg of DEX (DEX group, n=40) or the same amount of saline (Control group, n=40) under general anesthesia. The results showed that the time to first analgesic request was significantly longer in the DEX group than in the control group. The sevoflurane requirement for anesthesia and frequency of emergence agitation (EA) were also significantly lower in the DEX group. There was no difference in adverse events between the two groups. In conclusion, a dose of 1 µg/kg of caudal DEX prolonged the first analgesic request time, although the immediate postoperative pain scores were comparable in both groups. Furthermore, caudal DEX significantly reduced the sevoflurane requirement and the frequency of EA.-
dc.description.statementOfResponsibilityopen-
dc.format.extent1020~1025-
dc.relation.isPartOfBIOLOGICAL & PHARMACEUTICAL BULLETIN-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdrenergic alpha-2 Receptor Agonists/administration & dosage-
dc.subject.MESHAdrenergic alpha-2 Receptor Agonists/therapeutic use*-
dc.subject.MESHAmbulatory Care-
dc.subject.MESHAmides/administration & dosage-
dc.subject.MESHAmides/therapeutic use*-
dc.subject.MESHAnalgesics, Non-Narcotic/administration & dosage-
dc.subject.MESHAnalgesics, Non-Narcotic/therapeutic use*-
dc.subject.MESHAnesthetics, Local/administration & dosage-
dc.subject.MESHAnesthetics, Local/therapeutic use*-
dc.subject.MESHArterial Pressure/drug effects-
dc.subject.MESHChild, Preschool-
dc.subject.MESHDexmedetomidine/administration & dosage-
dc.subject.MESHDexmedetomidine/therapeutic use*-
dc.subject.MESHDouble-Blind Method-
dc.subject.MESHDrug Therapy, Combination-
dc.subject.MESHHeart Rate/drug effects-
dc.subject.MESHHumans-
dc.subject.MESHInfant-
dc.subject.MESHMale-
dc.subject.MESHOrchiopexy-
dc.subject.MESHPain Measurement-
dc.subject.MESHPain, Postoperative/drug therapy*-
dc.titleThe Effect of 1 µg/kg Dexmedetomidine Combined with High-Volume/Low-Concentration Caudal Ropivacaine in Children Undergoing Ambulatory Orchiopexy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Anesthesiology (마취통증의학)-
dc.contributor.googleauthorJang Eun Cho-
dc.contributor.googleauthorJi Young Kim-
dc.contributor.googleauthorSang Jae Park-
dc.contributor.googleauthorHae Keum Kil-
dc.identifier.doi10.1248/bpb.b15-00086-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00283-
dc.contributor.localIdA00977-
dc.relation.journalcodeJ00300-
dc.identifier.eissn1347-5215-
dc.identifier.pmid26133711-
dc.subject.keyworddexmedetomidine-
dc.subject.keywordcaudal block-
dc.subject.keywordchild-
dc.subject.keywordorchiopexy-
dc.contributor.alternativeNameKil, Hae Keum-
dc.contributor.alternativeNameKim, Ji Young-
dc.contributor.affiliatedAuthorKil, Hae Keum-
dc.contributor.affiliatedAuthorKim, Ji Young-
dc.rights.accessRightsfree-
dc.citation.volume38-
dc.citation.number7-
dc.citation.startPage1020-
dc.citation.endPage1025-
dc.identifier.bibliographicCitationBIOLOGICAL & PHARMACEUTICAL BULLETIN, Vol.38(7) : 1020-1025, 2015-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers

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